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복잡계자기조립연구단
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Guest-responsive, Non-proteolytic Harvest of a Cell-sheet using Controllable Host-guest Chemistry

DC Field Value Language
dc.contributor.authorKyeng Min Park-
dc.contributor.authorAnnadka Shrinidhi-
dc.contributor.authorJames Murray-
dc.contributor.authorKimoon Kim-
dc.date.available2019-05-02T08:10:49Z-
dc.date.created2019-04-03-
dc.date.issued2018-04-
dc.identifier.issn0021-2148-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/5789-
dc.description.abstractA new non-proteolytic method to harvest a cell-sheet was demonstrated using controllable host-guest interactions which can be dissociated by treating a strong guest on demand. Fibroblast cells (NIH3T3) were grown to confluence on a 1,6-diammoniumhexane conjugated hyaluronic acid (DAH-HA) polymer which was anchored to a cucurbit[7]uril (CB[7]) surface using the host-guest interaction between DAH and CB[7]. Treating with a strong guest allowed the cultured cells to be detached from the surface as a free standing sheet. This approach demonstrated the great potential of controllable host-guest chemistry as a novel tool for non-proteolytic harvesting of cell-sheets useful for regenerative therapy. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim-
dc.description.uri1-
dc.language영어-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectcucurbiturils-
dc.subjecthost-guest chemistry-
dc.subjecthyaluronic acid-
dc.subjectcell-sheets-
dc.subjectregenerative therapy-
dc.titleGuest-responsive, Non-proteolytic Harvest of a Cell-sheet using Controllable Host-guest Chemistry-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000430466900021-
dc.identifier.scopusid2-s2.0-85031105749-
dc.identifier.rimsid67750-
dc.contributor.affiliatedAuthorKyeng Min Park-
dc.contributor.affiliatedAuthorAnnadka Shrinidhi-
dc.contributor.affiliatedAuthorJames Murray-
dc.contributor.affiliatedAuthorKimoon Kim-
dc.identifier.doi10.1002/ijch.201700084-
dc.identifier.bibliographicCitationISRAEL JOURNAL OF CHEMISTRY, v.58, no.3-4, pp.461 - 465-
dc.citation.titleISRAEL JOURNAL OF CHEMISTRY-
dc.citation.volume58-
dc.citation.number3-4-
dc.citation.startPage461-
dc.citation.endPage465-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusCUCURBITURIL-
dc.subject.keywordPlusPOLYMER-
dc.subject.keywordPlusHYDROGELS-
dc.subject.keywordPlusSURFACES-
dc.subject.keywordPlusCOATINGS-
dc.subject.keywordPlusAFFINITY-
dc.subject.keywordPlusPLATFORM-
dc.subject.keywordPlusSYSTEMS-
dc.subject.keywordPlusPAIR-
dc.subject.keywordAuthorcucurbiturils-
dc.subject.keywordAuthorhost-guest chemistry-
dc.subject.keywordAuthorhyaluronic acid-
dc.subject.keywordAuthorcell-sheets-
dc.subject.keywordAuthorregenerative therapy-
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
300. K. M. Park, lsr. J. Chem., 2018.pdfDownload

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