Guest-responsive, Non-proteolytic Harvest of a Cell-sheet using Controllable Host-guest Chemistry
DC Field | Value | Language |
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dc.contributor.author | Kyeng Min Park | - |
dc.contributor.author | Annadka Shrinidhi | - |
dc.contributor.author | James Murray | - |
dc.contributor.author | Kimoon Kim | - |
dc.date.available | 2019-05-02T08:10:49Z | - |
dc.date.created | 2019-04-03 | - |
dc.date.issued | 2018-04 | - |
dc.identifier.issn | 0021-2148 | - |
dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/5789 | - |
dc.description.abstract | A new non-proteolytic method to harvest a cell-sheet was demonstrated using controllable host-guest interactions which can be dissociated by treating a strong guest on demand. Fibroblast cells (NIH3T3) were grown to confluence on a 1,6-diammoniumhexane conjugated hyaluronic acid (DAH-HA) polymer which was anchored to a cucurbit[7]uril (CB[7]) surface using the host-guest interaction between DAH and CB[7]. Treating with a strong guest allowed the cultured cells to be detached from the surface as a free standing sheet. This approach demonstrated the great potential of controllable host-guest chemistry as a novel tool for non-proteolytic harvesting of cell-sheets useful for regenerative therapy. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim | - |
dc.description.uri | 1 | - |
dc.language | 영어 | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | cucurbiturils | - |
dc.subject | host-guest chemistry | - |
dc.subject | hyaluronic acid | - |
dc.subject | cell-sheets | - |
dc.subject | regenerative therapy | - |
dc.title | Guest-responsive, Non-proteolytic Harvest of a Cell-sheet using Controllable Host-guest Chemistry | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.wosid | 000430466900021 | - |
dc.identifier.scopusid | 2-s2.0-85031105749 | - |
dc.identifier.rimsid | 67750 | - |
dc.contributor.affiliatedAuthor | Kyeng Min Park | - |
dc.contributor.affiliatedAuthor | Annadka Shrinidhi | - |
dc.contributor.affiliatedAuthor | James Murray | - |
dc.contributor.affiliatedAuthor | Kimoon Kim | - |
dc.identifier.doi | 10.1002/ijch.201700084 | - |
dc.identifier.bibliographicCitation | ISRAEL JOURNAL OF CHEMISTRY, v.58, no.3-4, pp.461 - 465 | - |
dc.citation.title | ISRAEL JOURNAL OF CHEMISTRY | - |
dc.citation.volume | 58 | - |
dc.citation.number | 3-4 | - |
dc.citation.startPage | 461 | - |
dc.citation.endPage | 465 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | CUCURBITURIL | - |
dc.subject.keywordPlus | POLYMER | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | COATINGS | - |
dc.subject.keywordPlus | AFFINITY | - |
dc.subject.keywordPlus | PLATFORM | - |
dc.subject.keywordPlus | SYSTEMS | - |
dc.subject.keywordPlus | PAIR | - |
dc.subject.keywordAuthor | cucurbiturils | - |
dc.subject.keywordAuthor | host-guest chemistry | - |
dc.subject.keywordAuthor | hyaluronic acid | - |
dc.subject.keywordAuthor | cell-sheets | - |
dc.subject.keywordAuthor | regenerative therapy | - |