Chronic and acute stress monitoring by electrophysiological signals from adrenal gland

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Title
Chronic and acute stress monitoring by electrophysiological signals from adrenal gland
Author(s)
Sung Hyuk Sunwoo; Ju Seung Lee; Sungjun Bae; Yiel Jae Shin; Chang Seong Kim; Soo Yeon Joo; Hong Sang Choi; Minah Suh; Soo Wan Kim; Young Jin Choi; Tae-il Kim
Publication Date
2019-01
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.116, no.4, pp.1146 - 1151
Publisher
NATL ACAD SCIENCES
Abstract
We present electrophysiological (EP) signals correlated with cellular cell activities in the adrenal cortex and medulla using an adrenal gland implantable flexible EP probe. With such a probe, we could observe the EP signals from the adrenal cortex and medulla in response to various stress stimuli, such as enhanced hormone activity with adrenocorticotropic hormone, a biomarker for chronic stress response, and an actual stress environment, like a forced swimming test. This technique could be useful to continuously monitor the elevation of cortisol level, a useful indicator of chronic stress that potentially causes various diseases.
URI
https://pr.ibs.re.kr/handle/8788114/5732
ISSN
0027-8424
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > Journal Papers (저널논문)
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