Precision genome engineering through adenine and cytosine base editing

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Title
Precision genome engineering through adenine and cytosine base editing
Author(s)
Jin Soo Kim
Publication Date
2018-03
Journal
Nature Plants, v.4, no.3, pp.148 - 151
Publisher
NATURE PUBLISHING GROUP
Abstract
Adenine base editors (ABEs), composed of an engineered deaminase and a catalytically impaired CRISPR–Cas9 variant, are powerful new tools for targeted base editing in cells and organisms. Together with cytosine base editors (CBEs), ABEs enable single-nucleotide conversions cleanly, efficiently and reversibly without double-stranded DNA cleavage, advancing genome editing in a new dimension. © 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved
URI
https://pr.ibs.re.kr/handle/8788114/5575
ISSN
2055-026X
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > Journal Papers (저널논문)
Files in This Item:
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