BROWSE

Related Scientist

Researcher

Manjare Sudesh Tulshiram
분자활성 촉매반응 연구단
more info

A selective fluorescent probe for cysteine and its imaging in live cells

Cited 19 time in webofscience Cited 0 time in scopus
174 Viewed 25 Downloaded
Title
A selective fluorescent probe for cysteine and its imaging in live cells
Author(s)
Youngsam Kim; Minsuk Choi; Seokjun Seo; a Sudesh T. Manjare; Sangyong Jon; David G. Churchill
Publication Date
2014
Journal
RSC ADVANCES, v.4, no.109, pp.64183 - 64186
Publisher
ROYAL SOC CHEMISTRY
Abstract
A probe for the detection of cysteine over homocysteine based on 2-(2'-hydroxyphenyl) benzothiazole (HBT) was prepared and used in confocal microscopy experiments. The probe was designed to block excited state intramolecular proton transfer (ESIPT). When bromopropionyl group protection is removed, HBT is recovered via nucleophilic substitution and intramolecular cyclization. The probe was found to have a detection limit of 2.8 mu M and exhibits a similar to 20-fold increase. The probe showed cell membrane permeability and efficacy in living Hep3B cells © The Royal Society of Chemistry 2014
URI
https://pr.ibs.re.kr/handle/8788114/4867
ISSN
2046-2069
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > Journal Papers (저널논문)
Files in This Item:
Chur_A selective fluorescent probe for cysteine and its imaging in live cells.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse