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manjare,sudeshtulshiram
분자활성촉매반응연구단
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A selective fluorescent probe for cysteine and its imaging in live cells

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dc.contributor.authorYoungsam Kim-
dc.contributor.authorMinsuk Choi-
dc.contributor.authorSeokjun Seo-
dc.contributor.authora Sudesh T. Manjare-
dc.contributor.authorSangyong Jon-
dc.contributor.authorDavid G. Churchill-
dc.date.available2018-07-18T02:10:06Z-
dc.date.created2018-03-15-
dc.date.issued2014-11-
dc.identifier.issn2046-2069-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/4867-
dc.description.abstractA probe for the detection of cysteine over homocysteine based on 2-(2'-hydroxyphenyl) benzothiazole (HBT) was prepared and used in confocal microscopy experiments. The probe was designed to block excited state intramolecular proton transfer (ESIPT). When bromopropionyl group protection is removed, HBT is recovered via nucleophilic substitution and intramolecular cyclization. The probe was found to have a detection limit of 2.8 mu M and exhibits a similar to 20-fold increase. The probe showed cell membrane permeability and efficacy in living Hep3B cells © The Royal Society of Chemistry 2014-
dc.language영어-
dc.publisherROYAL SOC CHEMISTRY-
dc.titleA selective fluorescent probe for cysteine and its imaging in live cells-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000345702900075-
dc.identifier.scopusid2-s2.0-84914172570-
dc.identifier.rimsid62574-
dc.date.tcdate2018-10-01-
dc.contributor.affiliatedAuthora Sudesh T. Manjare-
dc.identifier.doi10.1039/c4ra12981d-
dc.identifier.bibliographicCitationRSC ADVANCES, v.4, no.109, pp.64183 - 64186-
dc.relation.isPartOfRSC ADVANCES-
dc.citation.titleRSC ADVANCES-
dc.citation.volume4-
dc.citation.number109-
dc.citation.startPage64183-
dc.citation.endPage64186-
dc.date.scptcdate2018-10-01-
dc.description.wostc19-
dc.description.scptc18-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusASSISTED ELECTROSTATIC ATTRACTION-
dc.subject.keywordPlusPROTEIN FUNCTION-
dc.subject.keywordPlusLIVING CELLS-
dc.subject.keywordPlusHOMOCYSTEINE-
dc.subject.keywordPlusGLUTATHIONE-
dc.subject.keywordPlusMICROSCOPY-
dc.subject.keywordPlusCONJUGATE-
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > 1. Journal Papers (저널논문)
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