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IBS Publications RepositoryCenter for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단)1. Journal Papers (저널논문)

A selective fluorescent probe for cysteine and its imaging in live cells

DC Field	Value	Language
dc.contributor.author	Youngsam Kim	-
dc.contributor.author	Minsuk Choi	-
dc.contributor.author	Seokjun Seo	-
dc.contributor.author	a Sudesh T. Manjare	-
dc.contributor.author	Sangyong Jon	-
dc.contributor.author	David G. Churchill	-
dc.date.available	2018-07-18T02:10:06Z	-
dc.date.created	2018-03-15	-
dc.date.issued	2014-11	-
dc.identifier.issn	2046-2069	-
dc.identifier.uri	https://pr.ibs.re.kr/handle/8788114/4867	-
dc.description.abstract	A probe for the detection of cysteine over homocysteine based on 2-(2'-hydroxyphenyl) benzothiazole (HBT) was prepared and used in confocal microscopy experiments. The probe was designed to block excited state intramolecular proton transfer (ESIPT). When bromopropionyl group protection is removed, HBT is recovered via nucleophilic substitution and intramolecular cyclization. The probe was found to have a detection limit of 2.8 mu M and exhibits a similar to 20-fold increase. The probe showed cell membrane permeability and efficacy in living Hep3B cells © The Royal Society of Chemistry 2014	-
dc.language	영어	-
dc.publisher	ROYAL SOC CHEMISTRY	-
dc.title	A selective fluorescent probe for cysteine and its imaging in live cells	-
dc.type	Article	-
dc.type.rims	ART	-
dc.identifier.wosid	000345702900075	-
dc.identifier.scopusid	2-s2.0-84914172570	-
dc.identifier.rimsid	62574	-
dc.date.tcdate	2018-10-01	-
dc.contributor.affiliatedAuthor	a Sudesh T. Manjare	-
dc.identifier.doi	10.1039/c4ra12981d	-
dc.identifier.bibliographicCitation	RSC ADVANCES, v.4, no.109, pp.64183 - 64186	-
dc.relation.isPartOf	RSC ADVANCES	-
dc.citation.title	RSC ADVANCES	-
dc.citation.volume	4	-
dc.citation.number	109	-
dc.citation.startPage	64183	-
dc.citation.endPage	64186	-
dc.date.scptcdate	2018-10-01	-
dc.description.wostc	19	-
dc.description.scptc	18	-
dc.description.journalClass	1	-
dc.description.journalClass	1	-
dc.description.isOpenAccess	N	-
dc.description.journalRegisteredClass	scie	-
dc.description.journalRegisteredClass	scopus	-
dc.relation.journalWebOfScienceCategory	Chemistry, Multidisciplinary	-
dc.subject.keywordPlus	ASSISTED ELECTROSTATIC ATTRACTION	-
dc.subject.keywordPlus	PROTEIN FUNCTION	-
dc.subject.keywordPlus	LIVING CELLS	-
dc.subject.keywordPlus	HOMOCYSTEINE	-
dc.subject.keywordPlus	GLUTATHIONE	-
dc.subject.keywordPlus	MICROSCOPY	-
dc.subject.keywordPlus	CONJUGATE	-