BROWSE

Related Scientist

Researcher

뇌과학이미징연구단
뇌과학 이미징 연구단
more info

Insertable NO/CO Microsensors Recording Gaseous Vasomodulators Reflecting Differential Neuronal Activation Level with Respect to Seizure Focus

Cited 0 time in webofscience Cited 0 time in scopus
192 Viewed 29 Downloaded
Title
Insertable NO/CO Microsensors Recording Gaseous Vasomodulators Reflecting Differential Neuronal Activation Level with Respect to Seizure Focus
Author(s)
Yejin Ha; Youngmi Lee; Minah Suh
Publication Date
2017-09
Journal
ACS Chemical Neuroscience, v.8, no.9, pp.1853 - 1858
Publisher
AMER CHEMICAL SOC
Abstract
Nitric oxide (NO) and carbon monoxide (CO) are important signaling molecules shaping vasomodulation. This paper reports simultaneous in vivo monitoring of NO, CO and dendritic summation of action potential at three different cortical regions: seizure focus and two additional places, vertically and horizontally separated by 1.2 mm from the seizure focus, during epileptic seizure induced by 4-aminopyrindine injection. An amperometric dual microsensor having a high spatiotemporal resolution monitored fast and dynamic changes of NO and CO, and neural changes were recorded with a glass pipet electrode for local field potential (LFP). At all three locations, onsets and offsets of NO and CO changes well synchronized with fast LFP changes, while the patterns and concentrations of NO and CO changes were varied depending on the sensing locations. The insertable NO/CO dual microsensor was successful to measure intimately linked NO and CO in acute seizure events with high sensitivity, selectivity, and spatiotemporal resolution. © 2017 American Chemical Society
URI
https://pr.ibs.re.kr/handle/8788114/4077
ISSN
1948-7193
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > Journal Papers (저널논문)
Files in This Item:
34_이영미,서민아_Insertable NOCO Microsensors Recording Gaseous Vasomodulators...pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse