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Iterative C−H Functionalization Leading to Multiple Amidations of Anilides

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Title
Iterative C−H Functionalization Leading to Multiple Amidations of Anilides
Author(s)
Juhyeon Park; Jia Lee; Sukbok Chang
Subject
amidation, ; arenes, ; C−H activation, ; reaction mechanisms, ; ruthenium
Publication Date
2017-04
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.56, no.15, pp.4256 - 4260
Publisher
WILEY-V C H VERLAG GMBH
Abstract
Polyaminobenzenes were synthesized by the ruthenium-catalyzed iterative C−H amidation of anilides using dioxazolones as an amino source. This strategy could be implemented by the sequential activation of C−H bonds of formerly generated compounds by cascade chelation assistance of newly installed amide groups. Computational studies provided a rationale. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinhei
URI
https://pr.ibs.re.kr/handle/8788114/3728
DOI
10.1002/anie.201701138
ISSN
1433-7851
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > 1. Journal Papers (저널논문)
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