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Biosensors based on graphene oxide and its biomedical applicationHighly Cited Paper

Cited 132 time in webofscience Cited 149 time in scopus
1,454 Viewed 197 Downloaded
Title
Biosensors based on graphene oxide and its biomedical application
Author(s)
Jieon Lee; Jungho Kim; Seongchan Kim; Dal-Hee Min
Subject
Biomolecule, ; Biosensor, ; Electrochemistry, ; FRET, ; Graphene oxide, ; Hybrid nanomaterial, ; LDI-MS, ; SERS
Publication Date
2016-10
Journal
ADVANCED DRUG DELIVERY REVIEWS, v.105, pp.275 - 287
Publisher
ELSEVIER SCIENCE BV
Abstract
Graphene oxide (GO) is one of the most attributed materials for opening new possibilities in the development of next generation biosensors. Due to the coexistence of hydrophobic domain from pristine graphite structure and hydrophilic oxygen containing functional groups, GO exhibits good water dispersibility, biocompatibility, and high affinity for specific biomolecules as well as properties of graphene itself partly depending on preparation methods. These properties of GO provided a lot of opportunities for the development of novel biological sensing platforms, including biosensors based on fluorescence resonance energy transfer (FRET), laser desorption/ionization mass spectrometry (LDI-MS), surface-enhanced Raman spectroscopy (SERS), and electrochemical detection. In this review, we classify GO-based biological sensors developed so far by their signal generation strategy and provide the comprehensive overview of them. In addition, we offer insights into how the GO attributed in each sensor system and how they improved the sensing performance. © 2016 Elsevier B.V. All rights reserved.
URI
https://pr.ibs.re.kr/handle/8788114/3046
DOI
10.1016/j.addr.2016.06.001
ISSN
0169-409X
Appears in Collections:
Center for RNA Research(RNA 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
1-s2.0-S0169409X16301855-main (1).pdfDownload

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