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Proteomics in Rheumatoid Arthritis Research

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Title
Proteomics in Rheumatoid Arthritis Research
Author(s)
Yune-Jung Park; Min Kyung Chung; Daehee Hwang; Wan-Uk Kim
Publication Date
2015-08
Journal
Immune Network, v.15, no.4, pp.177 - 185
Publisher
대한면역학회
Abstract
Although rheumatoid arthritis (RA) is the most common chronic inflammatory autoimmune disease, diagnosis of RA is currently based on clinical manifestations, and there is no simple, practical assessment tool in the clinical field to assess disease activity and severity. Recently, there has been increasing interest in the discovery of new diagnostic RA biomarkers that can assist in evaluating disease activity, severity, and treatment response. Proteomics, the largescale study of the proteome, has emerged as a powerful technique for protein identification and characterization. For the past 10 years, proteomic techniques have been applied to different biological samples (synovial tissue/fluid, blood, and urine) from RA patients and experimental animal models. In this review, we summarize the current state of the application of proteomics in RA and its importance in identifying biomarkers and treatment targets.
URI
https://pr.ibs.re.kr/handle/8788114/1930
ISSN
1598-2629
Appears in Collections:
Center for Plant Aging Research (식물 노화·수명 연구단) > Journal Papers (저널논문)
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