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A biosensor for the detection of single base mismatches in microRNA

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Title
A biosensor for the detection of single base mismatches in microRNA
Author(s)
Jieon Lee; Park, G.; Dal-Hee Min
Publication Date
2015-10
Journal
CHEMICAL COMMUNICATIONS, v.51, no.78, pp.14597 - 14600
Publisher
ROYAL SOC CHEMISTRY
Abstract
Graphene oxide quenches fluorescence corresponding to only a mismatched target due to selective denaturing of the thermo-unstable duplex composed of probe peptide nucleic acid and single base mismatched target RNA and thus, the fluorescence signal only from perfectly matched target RNA is measured. This journal is © The Royal Society of Chemistry 2015
URI
https://pr.ibs.re.kr/handle/8788114/1853
ISSN
1359-7345
Appears in Collections:
Center for RNA Research(RNA 연구단) > Journal Papers (저널논문)
Files in This Item:
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