One-Pot Synthesis of Multifunctional Au@Graphene Oxide Nanocolloid Core@Shell Nanoparticles for Raman Bioimaging, Photothermal, and Photodynamic Therapy
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Title
- One-Pot Synthesis of Multifunctional Au@Graphene Oxide Nanocolloid Core@Shell Nanoparticles for Raman Bioimaging, Photothermal, and Photodynamic Therapy
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Author(s)
- Young-Kwan Kim; Hee-Kyung Na; Seongchan Kim; Hongje Jang; Sung-Jin Chang; Dal-Hee Min
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Publication Date
- 2015-06
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Journal
- SMALL, v.11, no.21, pp.2527 - 2535
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Publisher
- WILEY-V C H VERLAG GMBH
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Abstract
- The paper reports a facile one-pot synthesis of core@shell nanoparticles (NPs) composed of Au core and graphene oxide nanocolloid (GON) shell. Unique properties of Au NPs and GON can be incorporated into a single nanohybrid structure to provide desirable functions for theranosis such as localized surface plasmon resonance, Raman scattering, amphiphilic surface, and photothermal conversion. Synthesis of Au@GON NPs is achieved by simple one-pot reaction in aqueous phase utilizing GON as a reducing and stabilizing agent without any additional reducing agent. The zinc phthalocyanine, a photosensitizer, loaded Au@GON NPs show excellent multifunctional properties for combinational treatment of photothermal and photodynamic therapy in addition to Raman bioimaging with low cytotoxicity
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URI
- https://pr.ibs.re.kr/handle/8788114/1718
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DOI
- 10.1002/smll.201402269
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ISSN
- 1613-6810
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- Center for RNA Research(RNA 연구단) > 1. Journal Papers (저널논문)
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