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분자분광학및동력학연구단
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Long-term cargo tracking reveals intricate trafficking through active cytoskeletal networks in the crowded cellular environment

DC Field Value Language
dc.contributor.authorJin-Sung Park-
dc.contributor.authorIl-Buem Lee-
dc.contributor.authorHyeon-Min Moon-
dc.contributor.authorSeok-Cheol Hong-
dc.contributor.authorMinhaeng Cho-
dc.date.accessioned2024-01-12T22:00:27Z-
dc.date.available2024-01-12T22:00:27Z-
dc.date.created2023-11-28-
dc.date.issued2023-11-
dc.identifier.issn2041-1723-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/14573-
dc.description.abstractA eukaryotic cell is a microscopic world within which efficient material transport is essential. Yet, how a cell manages to deliver cellular cargos efficiently in a crowded environment remains poorly understood. Here, we used interferometric scattering microscopy to track unlabeled cargos in directional motion in a massively parallel fashion. Our label-free, cargo-tracing method revealed not only the dynamics of cargo transportation but also the fine architecture of the actively used cytoskeletal highways and the long-term evolution of the associated traffic at sub-diffraction resolution. Cargos frequently run into a blocked road or experience a traffic jam. Still, they have effective strategies to circumvent those problems: opting for an alternative mode of transport and moving together in tandem or migrating collectively. All taken together, a cell is an incredibly complex and busy space where the principle and practice of transportation intriguingly parallel those of our macroscopic world. © 2023, The Author(s).-
dc.language영어-
dc.publisherNature Research-
dc.titleLong-term cargo tracking reveals intricate trafficking through active cytoskeletal networks in the crowded cellular environment-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid001104729800013-
dc.identifier.scopusid2-s2.0-85176417967-
dc.identifier.rimsid82144-
dc.contributor.affiliatedAuthorJin-Sung Park-
dc.contributor.affiliatedAuthorIl-Buem Lee-
dc.contributor.affiliatedAuthorHyeon-Min Moon-
dc.contributor.affiliatedAuthorSeok-Cheol Hong-
dc.contributor.affiliatedAuthorMinhaeng Cho-
dc.identifier.doi10.1038/s41467-023-42347-7-
dc.identifier.bibliographicCitationNature Communications, v.14, no.1-
dc.relation.isPartOfNature Communications-
dc.citation.titleNature Communications-
dc.citation.volume14-
dc.citation.number1-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalWebOfScienceCategoryMultidisciplinary Sciences-
dc.subject.keywordPlusINTERFEROMETRIC SCATTERING MICROSCOPY-
dc.subject.keywordPlusLIVE-CELL-
dc.subject.keywordPlusVESICLE TRANSPORT-
dc.subject.keywordPlusAXONAL-TRANSPORT-
dc.subject.keywordPlusLABEL-FREE-
dc.subject.keywordPlusMOTORS-
dc.subject.keywordPlusLOCALIZATION-
dc.subject.keywordPlusKINESIN-
dc.subject.keywordPlusHITCHHIKING-
dc.subject.keywordPlusRESOLUTION-
Appears in Collections:
Center for Molecular Spectroscopy and Dynamics(분자 분광학 및 동력학 연구단) > 1. Journal Papers (저널논문)
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