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Depression in Adolescence and Brain-Derived Neurotrophic Factor

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Title
Depression in Adolescence and Brain-Derived Neurotrophic Factor
Author(s)
Boyoung Lee; Eunjin Shin; Inwoong Song; Bomi Chang
Publication Date
2022-07
Journal
Frontiers in Molecular Neuroscience, v.15
Publisher
Frontiers Media S.A.
Abstract
Copyright © 2022 Lee, Shin, Song and Chang.The incidence of depression among adolescents has been rapidly increasing in recent years. Environmental and genetic factors have been identified as important risk factors for adolescent depression. However, the mechanisms underlying the development of adolescent depression that are triggered by these risk factors are not well understood. Clinical and preclinical studies have focused more on adult depression, and differences in depressive symptoms between adolescents and adults make it difficult to adequately diagnose and treat adolescent depression. Brain-derived neurotrophic factor (BDNF) is known to play a critical role in the pathophysiology of many psychiatric disorders, including depression. However, there are still few studies on adolescent depression. Therefore, in this review paper, the causes and treatment of adolescent depression and the function of BDNF are investigated.
URI
https://pr.ibs.re.kr/handle/8788114/12901
DOI
10.3389/fnmol.2022.947192
ISSN
1662-5099
Appears in Collections:
Center for Cognition and Sociality(인지 및 사회성 연구단) > 1. Journal Papers (저널논문)
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