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Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing

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Title
Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing
Author(s)
Jeong-Yun Lee; Taeyi You; Choong-Wan Woo; Seong-Gi Kim
Publication Date
2022-10
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.20
Publisher
MDPI
Abstract
Sensory processing is a complex neurological process that receives, integrates, and responds to information from one's own body and environment, which is closely related to survival as well as neurological disorders. Brain-wide networks of sensory processing are difficult to investigate due to their dynamic regulation by multiple brain circuits. Optogenetics, a neuromodulation technique that uses light-sensitive proteins, can be combined with functional magnetic resonance imaging (ofMRI) to measure whole-brain activity. Since ofMRI has increasingly been used for investigating brain circuits underlying sensory processing for over a decade, we systematically reviewed recent ofMRI studies of sensory circuits and discussed the challenges of optogenetic fMRI in rodents.
URI
https://pr.ibs.re.kr/handle/8788114/12623
DOI
10.3390/ijms232012268
ISSN
1661-6596
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > 1. Journal Papers (저널논문)
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