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Viewpoints: Dual-blocking antibody against VEGF-A and angiopoietin-2 for treating vascular diseases of the eye
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- Title
- Viewpoints: Dual-blocking antibody against VEGF-A and angiopoietin-2 for treating vascular diseases of the eye
- Author(s)
- Gou Young Koh; Augustin, Hellmut G.; Campochiaro, Peter A.
- Publication Date
- 2022-05
- Journal
- Trends in Molecular Medicine, v.28, no.5, pp.347 - 349
- Publisher
- Elsevier Ltd
- Abstract
- © 2022 Elsevier LtdFaricimab, a bispecific antibody that targets the endothelial cell growth factors vascular endothelial growth factor-A (VEGF-A) and angiopoietin-2 (Angpt2), was recently approved for treating neovascular age-related macular degeneration and diabetic macular edema. Here, Koh and Augustin review how mechanistic studies have translated into therapies, while Campochiaro evaluates their impact and value for clinical practice.
- ISSN
- 1471-4914
- Appears in Collections:
- Center for Vascular Research(혈관 연구단) > 1. Journal Papers (저널논문)
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