BROWSE

Related Scientist

CNIR's photo.

CNIR
뇌과학 이미징 연구단
more info

ITEM VIEW & DOWNLOAD

Supramolecular assembly of protein building blocks: from folding to function

Cited 0 time in webofscience Cited 0 time in scopus
122 Viewed 0 Downloaded
Title
Supramolecular assembly of protein building blocks: from folding to function
Author(s)
Kim, Nam Hyeong; Choi, Hojae; Shahzad, Zafar Muhammad; Ki, Heesoo; Lee, Jaekyoung; Chae, Heeyeop; Yong Ho Kim
Publication Date
2022-01
Journal
NANO CONVERGENCE, v.9, no.1
Publisher
SPRINGER
Abstract
Several phenomena occurring throughout the life of living things start and end with proteins. Various proteins form one complex structure to control detailed reactions. In contrast, one protein forms various structures and implements other biological phenomena depending on the situation. The basic principle that forms these hierarchical structures is protein self-assembly. A single building block is sufficient to create homogeneous structures with complex shapes, such as rings, filaments, or containers. These assemblies are widely used in biology as they enable multivalent binding, ultra-sensitive regulation, and compartmentalization. Moreover, with advances in the computational design of protein folding and protein-protein interfaces, considerable progress has recently been made in the de novo design of protein assemblies. Our review presents a description of the components of supramolecular protein assembly and their application in understanding biological phenomena to therapeutics.
URI
https://pr.ibs.re.kr/handle/8788114/11186
DOI
10.1186/s40580-021-00294-3
ISSN
2196-5404
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse