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MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing
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- Title
- MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing
- Author(s)
- Jae-Sung Woo; Vic Narry Kim
- Subject
- Biogenesis
- Publication Date
- 2014-03
- Journal
- DEVELOPMENTAL CELL, v.28, no.5, pp.477 - 478
- Publisher
- CELL PRESS
- Abstract
- MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.
- ISSN
- 1534-5807
- Appears in Collections:
- Center for RNA Research(RNA 연구단) > 1. Journal Papers (저널논문)
- Files in This Item:
- RNA 20_Develpmental Cell.pdfDownload
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Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
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