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MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

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Title
MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing
Author(s)
Jae-Sung Woo; Kim , Vic Narry
Publication Date
2014-03
Journal
DEVELOPMENTAL CELL, v.28, no.5, pp.477 - 478
Publisher
CELL PRESS
Abstract
MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.
URI
https://pr.ibs.re.kr/handle/8788114/1098
ISSN
1534-5807
Appears in Collections:
Center for RNA Research(RNA 연구단) > Journal Papers (저널논문)
Files in This Item:
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