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Bioengineering platforms for cell therapeutics derived from pluripotent and direct reprogramming

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Title
Bioengineering platforms for cell therapeutics derived from pluripotent and direct reprogramming
Author(s)
Yoonhee Jin; Seung-Woo Cho
Publication Date
2021-09
Journal
APL Bioengineering, v.5, no.3
Publisher
American Institute of Physics Inc.
Abstract
© 2021 Author(s).Pluripotent and direct reprogramming technologies hold great potential for tissue repair and restoration of tissue and organ function. The implementation of induced pluripotent stem cells and directly reprogrammed cells in biomedical research has resulted in a significant leap forward in the highly promising area of regenerative medicine. While these therapeutic strategies are promising, there are several obstacles to overcome prior to the introduction of these therapies into clinical settings. Bioengineering technologies, such as biomaterials, bioprinting, microfluidic devices, and biostimulatory systems, can enhance cell viability, differentiation, and function, in turn the efficacy of cell therapeutics generated via pluripotent and direct reprogramming. Therefore, cellular reprogramming technologies, in combination with tissue-engineering platforms, are poised to overcome current bottlenecks associated with cell-based therapies and create new ways of producing engineered tissue substitutes.
URI
https://pr.ibs.re.kr/handle/8788114/10127
DOI
10.1063/5.0040621
ISSN
2473-2877
Appears in Collections:
Center for Nanomedicine (나노의학 연구단) > 1. Journal Papers (저널논문)
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