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Publication Date2024-05
Concurrent Optimizations of Efficacy and Blood-Brain Barrier Permeability in New Macrocyclic LRRK2 Inhibitors for Potential Parkinson’s Disease Therapeutics
Kewon Kim; Ahyoung Jang; Shin, Hochul, et al
Journal of Medicinal Chemistry, v.67, no.7647, pp.7647 - 7662
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Publication Date2020-12
Rational Computational Design of Fourth-Generation EGFR Inhibitors to Combat Drug-Resistant Non-Small Cell Lung Cancer
Park, Hwangseo; Hoi-Yun Jung; Kewon Kim, et al
International Journal of Molecular Sciences, v.21, no.23, pp.1 - 23
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Publication Date2022-11
Structure-Based Virtual Screening and De Novo Design to Identify Submicromolar Inhibitors of G2019S Mutant of Leucine-Rich Repeat Kinase 2
Park, Hwangseo; Kim, Taeho; Kewon Kim, et al
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.21
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Publication Date2022-09
Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton's Tyrosine Kinase
Kim, Taeho; Kewon Kim; Inyoung Park, et al
JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.62, no.18, pp.4500 - 4511