BROWSE

Related Scientist

Kim, Jin Soo's photo.

Kim, Jin Soo
유전체 교정 연구단
more info

ITEM VIEW & DOWNLOAD

Web-based CRISPR Toolkits: Cas-OFFinder, cas-designer, and cas-analyzer

DC Field Value Language
dc.contributor.authorGue-Ho Hwang-
dc.contributor.authorJin-Soo Kim-
dc.contributor.authorSangsu Bae-
dc.date.accessioned2021-07-02T08:30:00Z-
dc.date.accessioned2021-07-02T08:30:00Z-
dc.date.available2021-07-02T08:30:00Z-
dc.date.available2021-07-02T08:30:00Z-
dc.date.created2020-11-09-
dc.date.issued2021-01-
dc.identifier.issn1064-3745-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/9821-
dc.description.abstract© 2021, Springer Science+Business Media, LLC, part of Springer Nature.The CRISPR-Cas system facilitates highly efficient genome editing; thus, it has been applied in many research fields such as biological science, medicine, and gene therapy. However, CRISPR nucleases can cleave off-target sites as well as on-target sites, causing unwanted mutations. Furthermore, after CRISPR treatments are delivered into cells or organisms, it is important to estimate the resulting mutation rates and to determine the patterns of mutations, but these tasks can be difficult. To address these issues, we have developed a tool for identifying potential off-target sites (Cas-OFFinder), a tool for designing CRISPR targets (Cas-Designer), and an assessment tool (Cas-Analyzer). These programs are all implemented on our website so that researchers can easily design CRISPR guide RNAs and assess the resulting mutations by simply clicking on the appropriate buttons; no login process is required-
dc.language영어-
dc.publisherHumana Press, Inc.-
dc.titleWeb-based CRISPR Toolkits: Cas-OFFinder, cas-designer, and cas-analyzer-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.scopusid2-s2.0-85091053089-
dc.identifier.rimsid73366-
dc.contributor.affiliatedAuthorJin-Soo Kim-
dc.identifier.doi10.1007/978-1-0716-0687-2_2-
dc.identifier.bibliographicCitationMethods in molecular biology (Clifton, N.J.), v.2162, pp.23 - 33-
dc.relation.isPartOfMethods in molecular biology (Clifton, N.J.)-
dc.citation.titleMethods in molecular biology (Clifton, N.J.)-
dc.citation.volume2162-
dc.citation.startPage23-
dc.citation.endPage33-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordAuthorCRISPR-cas system-
dc.subject.keywordAuthorOff-target-
dc.subject.keywordAuthorWeb-based tool-
dc.subject.keywordAuthorCas-analyzer-
dc.subject.keywordAuthorCas-designer-
dc.subject.keywordAuthorCas-OFFinder-
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse