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lhee,sangmoon
식물노화·수명연구단
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Spatial localization of charged molecules by salt ions in oil-confined water microdroplets

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dc.contributor.authorSangMoon Lhee-
dc.contributor.authorJae Kyoo Lee-
dc.contributor.authorJooyoun Kang-
dc.contributor.authorShota Kato-
dc.contributor.authorSunhee Kim-
dc.contributor.authorRichard N. Zare-
dc.contributor.authorHong Gil Nam-
dc.date.accessioned2020-12-22T02:32:01Z-
dc.date.accessioned2020-12-22T02:32:01Z-
dc.date.available2020-12-22T02:32:01Z-
dc.date.available2020-12-22T02:32:01Z-
dc.date.created2020-11-16-
dc.date.issued2020-10-
dc.identifier.issn2375-2548-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/7594-
dc.description.abstract© 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. Cells contain more than 100 mM salt ions that are typically confined to dimensions of 5 to 10 micrometers by a hydrophobic cellular membrane. We found that in aqueous microdroplets having the same size as cells and that are confined in hydrocarbon oil, negatively charged molecules were distributed rather uniformly over the interior of the microdroplet, whereas positively charged molecules were localized at and near the surface. However, the addition of salt (NaCl) to the microdroplet caused all charged molecules to be localized near the oil-water interface. This salt-induced relocalization required less salt concentration in microdroplets compared to bulk water. Moreover, the localization became more prominent as the size of the microdroplet was reduced. The relocatization also critically depended on the type of oil. Our results imply that salt ions and different hydrophobic interfaces together may govern the local distribution of charged biomolecules in confined intracellular environments-
dc.description.uri1-
dc.language영어-
dc.publisherAMER ASSOC ADVANCEMENT SCIENCE-
dc.titleSpatial localization of charged molecules by salt ions in oil-confined water microdroplets-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000579161500004-
dc.identifier.scopusid2-s2.0-85092685089-
dc.identifier.rimsid73387-
dc.contributor.affiliatedAuthorSangMoon Lhee-
dc.contributor.affiliatedAuthorJooyoun Kang-
dc.contributor.affiliatedAuthorShota Kato-
dc.contributor.affiliatedAuthorSunhee Kim-
dc.contributor.affiliatedAuthorHong Gil Nam-
dc.identifier.doi10.1126/sciadv.aba0181-
dc.identifier.bibliographicCitationSCIENCE ADVANCES, v.6, no.41, pp.1 - 9-
dc.citation.titleSCIENCE ADVANCES-
dc.citation.volume6-
dc.citation.number41-
dc.citation.startPage1-
dc.citation.endPage9-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Appears in Collections:
Center for Plant Aging Research (식물 노화·수명 연구단) > 1. Journal Papers (저널논문)
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