BROWSE

Related Scientist

SYNAPSE's photo.

SYNAPSE
시냅스 뇌질환 연구단
more info

ITEM VIEW & DOWNLOAD

Active maintenance of eligibility trace in rodent prefrontal cortex

Cited 0 time in webofscience Cited 0 time in scopus
15 Viewed 0 Downloaded
Title
Active maintenance of eligibility trace in rodent prefrontal cortex
Author(s)
Dong-Hyun Lim; Young Ju Yoon; Eunsil Her; Suehee Huh; Min Whan Jung
Publication Date
2020-11
Journal
SCIENTIFIC REPORTS, v.10, no.1, pp.18860 - 18860
Publisher
NATURE PUBLISHING GROUP
Abstract
© 2020, The Author(s). Even though persistent neural activity has been proposed as a mechanism for maintaining eligibility trace, direct empirical evidence for active maintenance of eligibility trace has been lacking. We recorded neuronal activity in the medial prefrontal cortex (mPFC) in rats performing a dynamic foraging task in which a choice must be remembered until its outcome on the timescale of seconds for correct credit assignment. We found that mPFC neurons maintain significant choice signals during the time period between action selection and choice outcome. We also found that neural signals for choice, outcome, and action value converge in the mPFC when choice outcome was revealed. Our results indicate that the mPFC maintains choice signals necessary for temporal credit assignment in the form of persistent neural activity in our task. They also suggest that the mPFC might update action value by combining actively maintained eligibility trace with action value and outcome signals
URI
https://pr.ibs.re.kr/handle/8788114/7558
DOI
10.1038/s41598-020-75820-0
ISSN
2045-2322
Appears in Collections:
Center for Synaptic Brain Dysfunctions(시냅스 뇌질환 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse