Strategic Approach to the Metamorphosis of γ-Lactones to NH γ-Lactams via Reductive Cleavage and C-H Amidation
DC Field | Value | Language |
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dc.contributor.author | Hoi-Yun Jung | - |
dc.contributor.author | Sukbok Chang | - |
dc.contributor.author | Sungwoo Hong | - |
dc.date.available | 2019-11-13T07:32:39Z | - |
dc.date.created | 2019-09-24 | - |
dc.date.issued | 2019-09 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/6435 | - |
dc.description.abstract | © 2019 American Chemical Society.A new approach has elaborated on the conversion of γ-lactones to the corresponding NH γ-lactams that can serve as γ-lactone bioisosteres. This approach consists of reductive C-O cleavage and an Ir-catalyzed C-H amidation, offering a powerful synthetic tool for accessing a wide range of valuable NH γ-lactam building blocks starting from γ-lactones. The synthetic utility was further demonstrated by the late-stage transformation of complex bioactive molecules and the asymmetric transformation | - |
dc.description.uri | 1 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Strategic Approach to the Metamorphosis of γ-Lactones to NH γ-Lactams via Reductive Cleavage and C-H Amidation | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.wosid | 000485089300103 | - |
dc.identifier.scopusid | 2-s2.0-85071653404 | - |
dc.identifier.rimsid | 69797 | - |
dc.contributor.affiliatedAuthor | Hoi-Yun Jung | - |
dc.contributor.affiliatedAuthor | Sukbok Chang | - |
dc.contributor.affiliatedAuthor | Sungwoo Hong | - |
dc.identifier.doi | 10.1021/acs.orglett.9b02673 | - |
dc.identifier.bibliographicCitation | ORGANIC LETTERS, v.21, no.17, pp.7099 - 7103 | - |
dc.citation.title | ORGANIC LETTERS | - |
dc.citation.volume | 21 | - |
dc.citation.number | 17 | - |
dc.citation.startPage | 7099 | - |
dc.citation.endPage | 7103 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | ANALOGS | - |
dc.subject.keywordPlus | ACIDS | - |