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habib,omer
유전체교정연구단
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Generation of a Nrf2 homozygous knockout human embryonic stem cell line using CRISPR/Cas9

DC Field Value Language
dc.contributor.authorKim, SJ-
dc.contributor.authorOmer Habib-
dc.contributor.authorJin-Soo Kim-
dc.contributor.authorHan, HW-
dc.contributor.authorKoo, SK-
dc.contributor.authorKim, JH-
dc.date.available2019-05-02T08:11:05Z-
dc.date.created2017-04-24-
dc.date.issued2017-03-
dc.identifier.issn1873-5061-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/5802-
dc.description.abstractNuclear factor erythroid 2-related factor 2 (NFE2L2 or Nrf2) is a well-known transcription factor that regulates the expression of a large number of anti-oxidant genes in mammalian cells (J.H. Kim et al., 2014). Here, we generated a homozygous Nrf2 knockout human embryonic stem cell (hESC) line, H9Nrf2KO-A13, using the CRISPR/Cas9 genome editing method. The Nrf2 homozygous knockout H9 cell line maintains pluripotency, differentiation potential into three germ layers, and a normal karyotype. (C) 2016 The Author(s). Published by Elsevier B.V-
dc.description.uri1-
dc.language영어-
dc.publisherELSEVIER SCIENCE BV-
dc.titleGeneration of a Nrf2 homozygous knockout human embryonic stem cell line using CRISPR/Cas9-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000397450700010-
dc.identifier.scopusid2-s2.0-85020319545-
dc.identifier.rimsid59207-
dc.contributor.affiliatedAuthorOmer Habib-
dc.contributor.affiliatedAuthorJin-Soo Kim-
dc.identifier.doi10.1016/j.scr.2016.12.027-
dc.identifier.bibliographicCitationSTEM CELL RESEARCH, v.19, pp.46 - 48-
dc.citation.titleSTEM CELL RESEARCH-
dc.citation.volume19-
dc.citation.startPage46-
dc.citation.endPage48-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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성과추가_1703_사사X_김진수_StemCellResearch_2.pdfDownload

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