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A one-step method for covalent bond immobilization of biomolecules on silica operated in aqueous solution

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Title
A one-step method for covalent bond immobilization of biomolecules on silica operated in aqueous solution
Author(s)
Yong-Kyun Sim; Heetae Jung; Su Hyun Kim; Jung Woo Park; Woo-Jin Park; Chul-Ho Jun
Publication Date
2018
Journal
Chemical Science, v.9, no.41, pp.7981 - 7985
Publisher
ROYAL SOC CHEMISTRY
Abstract
A simple, one-step method for covalent bond immobilization of biomolecules on silica operated in water is described. In the approach, an NHS-ester linked methallylsilane is utilized as a bifunctional linker to couple the biomolecule to the silica surface. Weak organic acid such as acetic acid activates the silica surface enough to react with bifunctional linker without destroying activity of biomolecule. © The Royal Society of Chemistry 2018
URI
https://pr.ibs.re.kr/handle/8788114/5303
ISSN
2041-6520
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > Journal Papers (저널논문)
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