BROWSE

Related Scientist

rna's photo.

rna
rna연구단
more info

ITEM VIEW & DOWNLOAD

Synthesis of porous Pd nanoparticles by therapeutic chaga extract for highly efficient tri-modal cancer treatment

DC Field Value Language
dc.contributor.authorYeong-Gyu Gil-
dc.contributor.authorSeounghun Kang-
dc.contributor.authorAri Chae-
dc.contributor.authorYoung-Kwan Kim-
dc.contributor.authorDal-Hee Min-
dc.contributor.authorHongje Jang-
dc.date.available2019-01-03T05:31:10Z-
dc.date.created2018-11-22-
dc.date.issued2018-11-
dc.identifier.issn2040-3364-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/5096-
dc.description.abstractPorous palladium nanoparticles were designed and synthesized to maximize the pharmacological activity of the chaga mushroom (Inonotus obliquus) extract, which has anticancer and antibacterial activities. In the present study, we synthesized anisotropic porous Pd nanostructures with ultraviolet-visible-near infrared whole wavelength region absorption using chaga extract concentration-dependent reductant-mediated synthesis. The porous Pd nanoparticles exhibited a surface chaga extract-derived anticancer effect, controlled delivery of doxorubicin through electrostatic interaction, and a photothermal conversion effect under 808 nm laser irradiation. The combined application of the three cancer treatment approaches clearly demonstrated the feasibility of synergistic tri-modal therapy. The present platform using Pd, which is a key constituent element of nanocatalysts but is not commonly used in biological applications, suggests numerous applications utilizing Pd nanostructures, as well as the potential development of new cancer therapies. © 2018 The Royal Society of Chemistry-
dc.language영어-
dc.publisherROYAL SOC CHEMISTRY-
dc.titleSynthesis of porous Pd nanoparticles by therapeutic chaga extract for highly efficient tri-modal cancer treatment-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000449699400015-
dc.identifier.scopusid2-s2.0-85055790379-
dc.identifier.rimsid66120-
dc.contributor.affiliatedAuthorSeounghun Kang-
dc.contributor.affiliatedAuthorDal-Hee Min-
dc.identifier.doi10.1039/c8nr07172a-
dc.identifier.bibliographicCitationNANOSCALE, v.10, no.42, pp.19810 - 19817-
dc.relation.isPartOfNANOSCALE-
dc.citation.titleNANOSCALE-
dc.citation.volume10-
dc.citation.number42-
dc.citation.startPage19810-
dc.citation.endPage19817-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Appears in Collections:
Center for RNA Research(RNA 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
c8nr07172a.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse