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Synthesis of biologically-active reduced graphene oxide by using fucoidan as a multifunctional agent for combination cancer therapy

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dc.contributor.authorSeonghun Kang-
dc.contributor.authorYu Lim Hong-
dc.contributor.authorBon-Cheol Ku-
dc.contributor.authorSeunghyun Lee-
dc.contributor.authorSeomgwoo Ryu-
dc.contributor.authorDal-hee Min-
dc.contributor.authorHongje Jang-
dc.contributor.authorYoung-kwan Kim-
dc.date.available2019-01-03T05:30:44Z-
dc.date.created2018-10-15-
dc.date.issued2018-11-
dc.identifier.issn0957-4484-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/5070-
dc.description.abstractA therapeutic reduced graphene oxide (RGO) is synthesized by using fucoidan (Fu) as the reducing and surface functionalizing agent. The synthesized Fu-RGO exhibits promising characteristics for therapeutic applications such as high dispersity in aqueous media, biocompatibility, selective cytotoxicity to cancer cells, high loading capacity of the anticancer drug, and photothermal conversion effect. Therefore, Fu-GO is successfully harnessed as a combinatorial cancer treatment platform through bio-functional (Fu), chemo (doxorubicin (Dox)) and photothermal (RGO with near-infrared irradiation) modalities. © 2018 IOP Publishing Ltd Printed in the UK-
dc.description.uri1-
dc.language영어-
dc.publisherIOP PUBLISHING LTD-
dc.subjectfucoidan-
dc.subjectgraphene oxide-
dc.subjectreduction-
dc.subjectsurface functionalization-
dc.subjectcancer therapy-
dc.titleSynthesis of biologically-active reduced graphene oxide by using fucoidan as a multifunctional agent for combination cancer therapy-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000445953400002-
dc.identifier.scopusid2-s2.0-85054534896-
dc.identifier.rimsid65710-
dc.contributor.affiliatedAuthorDal-hee Min-
dc.identifier.doi10.1088/1361-6528/aadfa5-
dc.identifier.bibliographicCitationNANOTECHNOLOGY, v.29, no.47, pp.475604-
dc.citation.titleNANOTECHNOLOGY-
dc.citation.volume29-
dc.citation.number47-
dc.citation.startPage475604-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordPlusDRUG-DELIVERY-
dc.subject.keywordPlusGOLD NANOPARTICLES-
dc.subject.keywordPlusCELLS-
dc.subject.keywordPlusREDUCTION-
dc.subject.keywordPlusANTICOAGULANT-
dc.subject.keywordPlusINDUCTION-
dc.subject.keywordPlusAPOPTOSIS-
dc.subject.keywordPlusMOLECULE-
dc.subject.keywordAuthorfucoidan-
dc.subject.keywordAuthorgraphene oxide-
dc.subject.keywordAuthorreduction-
dc.subject.keywordAuthorsurface functionalization-
dc.subject.keywordAuthorcancer therapy-
Appears in Collections:
Center for RNA Research(RNA 연구단) > 1. Journal Papers (저널논문)
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