ERCC1-XPF endonuclease-positioned to cut
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Orlando D Scharer | - |
dc.date.available | 2018-01-04T06:45:16Z | - |
dc.date.created | 2017-08-29 | - |
dc.date.issued | 2017-07 | - |
dc.identifier.issn | 0261-4189 | - |
dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/4154 | - |
dc.description.abstract | To counteract damage to our genomes, numerous endo-and exonucleases incise the DNA backbone to remove damaged and aberrant DNA structures. It is imperative that such incisions be very tightly controlled, as unwanted DNA breaks are a key source of genome instability. Two new papers in The EMBO Journal shed light on how the activity of one such nuclease-ERCC1-XPF, an enzyme involved in various DNA repair pathways-is regulated to perform incision in the vicinity of DNA interstrand crosslinks. (c) 2017 The Author | - |
dc.description.uri | 1 | - |
dc.language | 영어 | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.title | ERCC1-XPF endonuclease-positioned to cut | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.wosid | 000405478400001 | - |
dc.identifier.scopusid | 2-s2.0-85021447721 | - |
dc.identifier.rimsid | 59989 | ko |
dc.date.tcdate | 2018-10-01 | - |
dc.contributor.affiliatedAuthor | Orlando D Scharer | - |
dc.identifier.doi | 10.15252/embj.201797489 | - |
dc.identifier.bibliographicCitation | EMBO JOURNAL, v.36, no.14, pp.1993 - 1995 | - |
dc.citation.title | EMBO JOURNAL | - |
dc.citation.volume | 36 | - |
dc.citation.number | 14 | - |
dc.citation.startPage | 1993 | - |
dc.citation.endPage | 1995 | - |
dc.date.scptcdate | 2018-10-01 | - |
dc.description.wostc | 1 | - |
dc.description.scptc | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | NUCLEOTIDE EXCISION-REPAIR | - |
dc.subject.keywordPlus | GENOME STABILITY | - |
dc.subject.keywordPlus | FANCONI-ANEMIA | - |
dc.subject.keywordPlus | NUCLEASE | - |
dc.subject.keywordPlus | XPF-ERCC1 | - |
dc.subject.keywordPlus | COMPLEX | - |
dc.subject.keywordPlus | SLX4 | - |