Modelling cytokine signalling networks

Abstract

Although an imbalance between proinflammatory and anti-inflammatory cytokines has been implicated in rheumatoid arthritis (RA), the identification of specific cytokines regulating RA pathophysiotogy is still challenging. Modelling cytokine signalling networks and evaluating associated pathway activities might facilitate the effective identification of cytokines for treatment and prevention of RA. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.