Synthesis of Degradable Poly[(Ethylene Glycol)-co-(Glycolic Acid)] via the Post-Polymerization Oxyfunctionalization of Poly(Ethylene Glycol)
DC Field | Value | Language |
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dc.contributor.author | Di Liu | - |
dc.contributor.author | Christopher W. Bielawski | - |
dc.date.available | 2017-01-20T08:31:22Z | - |
dc.date.created | 2016-12-19 | - |
dc.date.issued | 2016-10 | - |
dc.identifier.issn | 1022-1336 | - |
dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/3260 | - |
dc.description.abstract | To enhance the limited degradability of poly(ethylene glycol) (PEG), a straightforward method of synthesizing poly[(ethylene glycol)-co-(glycolic acid)] (P(EG-co-GA)) via a ruthenium- catalyzed, post-polymerization oxyfunctionalization of various PEGs is developed. Using this method, a set of copolymers with GA compositions of up to 8 mol% are prepared with minimal reduction in molecular weight (<10%) when compared to their commercially available starting materials. The P(EG-co-GA) copolymers are shown to undergo hydrolysis under mild conditions. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim | - |
dc.description.uri | 1 | - |
dc.language | 영어 | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | biodegradable polymers | - |
dc.subject | drug delivery systems | - |
dc.subject | poly(ethylene glycol) | - |
dc.subject | post-polymerization modification | - |
dc.subject | ruthenium | - |
dc.title | Synthesis of Degradable Poly[(Ethylene Glycol)-co-(Glycolic Acid)] via the Post-Polymerization Oxyfunctionalization of Poly(Ethylene Glycol) | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.wosid | 000386630800005 | - |
dc.identifier.scopusid | 2-s2.0-85027941341 | - |
dc.identifier.rimsid | 57980 | ko |
dc.date.tcdate | 2018-10-01 | - |
dc.contributor.affiliatedAuthor | Christopher W. Bielawski | - |
dc.identifier.doi | 10.1002/marc.201600336 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR RAPID COMMUNICATIONS, v.37, no.19, pp.1587 - 1592 | - |
dc.citation.title | MACROMOLECULAR RAPID COMMUNICATIONS | - |
dc.citation.volume | 37 | - |
dc.citation.number | 19 | - |
dc.citation.startPage | 1587 | - |
dc.citation.endPage | 1592 | - |
dc.date.scptcdate | 2018-10-01 | - |
dc.description.wostc | 4 | - |
dc.description.scptc | 5 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | RUTHENIUM TETROXIDE | - |
dc.subject.keywordPlus | PEGYLATION | - |
dc.subject.keywordPlus | OXIDATION | - |
dc.subject.keywordPlus | PEG | - |
dc.subject.keywordPlus | THERAPEUTICS | - |
dc.subject.keywordAuthor | biodegradable polymers | - |
dc.subject.keywordAuthor | drug delivery systems | - |
dc.subject.keywordAuthor | poly(ethylene glycol) | - |
dc.subject.keywordAuthor | post-polymerization modification | - |
dc.subject.keywordAuthor | ruthenium | - |