BROWSE

Related Scientist

Researcher

Charles Surh
면역 미생물 공생 연구단
more info

Harnessing the IL-7/IL-7R alpha axis to improve tumor immunotherapy

DC Field Value Language
dc.contributor.authorJohnson, C. Bryce-
dc.contributor.authorWrangle, John-
dc.contributor.authorMehrotra, Shikhar-
dc.contributor.authorLi, Zihai-
dc.contributor.authorPaulos, Chrystal M.-
dc.contributor.authorCole, David J.-
dc.contributor.authorCharles D. Surh-
dc.contributor.authorRubinstein, Mark P.-
dc.date.available2017-01-06T02:05:13Z-
dc.date.created2017-01-05-
dc.date.issued2016-05-
dc.identifier.issn2162-402X-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/3172-
dc.description.abstractIL-7 and IL-15 are critical for supporting T cells transferred into a lymphopenic environment. As activated CD8(+) T cells downregulate IL-7R alpha, it is thought IL-15 is more important. However, we find that CD8(+) T cells activated with IL-12 have elevated IL-7R alpha and rely on IL-7 for persistence and antitumor immunity. © 2016 Taylor & Francis Group, LLC-
dc.languageENG-
dc.titleHarnessing the IL-7/IL-7R alpha axis to improve tumor immunotherapy-
dc.typeArticle-
dc.type.rimsA-
dc.identifier.wosid000379162200024-
dc.identifier.scopusid2-s2.0-84964627091-
dc.description.wostc2-
dc.date.tcdate2018-10-01-
dc.date.scptcdate2018-10-01-
dc.subject.keywordAdoptive cellular therapy-
dc.subject.keywordCD8-
dc.subject.keywordIL-7-
dc.subject.keywordIL-7Ra-
dc.subject.keywordIL-15-
dc.contributor.affiliatedAuthorCharles D. Surh-
dc.identifier.bibliographicCitationOncoImmunology, v.5, no.5, pp.e1122865 --
dc.description.scptc2-
Appears in Collections:
Academy of Immunology and Microbiology(면역 미생물 공생 연구단) > Journal Papers (저널논문)
Files in This Item:
Harnessing the IL-7IL-7Rα axis to improve tumor immunotherapy_Charles D. Surh.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse