Asymmetric C–H functionalization of cyclopropanes using an isoleucine-NH2 bidentate directing group
DC Field | Value | Language |
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dc.contributor.author | Jinhee Kim | - |
dc.contributor.author | Mikyung Sim | - |
dc.contributor.author | Namhoon Kim | - |
dc.contributor.author | Sungwoo Hong | - |
dc.date.available | 2016-01-07T09:16:22Z | - |
dc.date.created | 2015-06-16 | - |
dc.date.issued | 2015-06 | - |
dc.identifier.issn | 2041-6520 | - |
dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/2178 | - |
dc.description.abstract | The systematic investigation of substrate-bound a-amino acid auxiliaries has resulted in catalytic asymmetric C–H functionalization of cyclopropanes enabled by amino acid amides as chiral bidentate directing groups. The use of an Ile-NH2 auxiliary embedded in the substrate provided excellent levels of asymmetric induction (diastereomeric ratio of up to 72 : 1) in the Pd(II)-catalyzed b-methylene C(sp3)–H bond activation of cyclopropanes and cross-coupling with aryl iodides. | - |
dc.description.uri | 1 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Asymmetric C–H functionalization of cyclopropanes using an isoleucine-NH2 bidentate directing group | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.wosid | 000354815600046 | - |
dc.identifier.scopusid | 2-s2.0-84929598029 | - |
dc.identifier.rimsid | 20313 | ko |
dc.date.tcdate | 2018-10-01 | - |
dc.contributor.affiliatedAuthor | Jinhee Kim | - |
dc.contributor.affiliatedAuthor | Mikyung Sim | - |
dc.contributor.affiliatedAuthor | Namhoon Kim | - |
dc.contributor.affiliatedAuthor | Sungwoo Hong | - |
dc.identifier.doi | 10.1039/c5sc01137j | - |
dc.identifier.bibliographicCitation | CHEMICAL SCIENCE, v.6, no.6, pp.3611 - 3616 | - |
dc.citation.title | CHEMICAL SCIENCE | - |
dc.citation.volume | 6 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 3611 | - |
dc.citation.endPage | 3616 | - |
dc.date.scptcdate | 2018-10-01 | - |
dc.description.wostc | 39 | - |
dc.description.scptc | 40 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |