BROWSE

Related Scientist

Researcher

분자활성 촉매반응 연구단
분자활성 촉매반응 연구단
more info

Rh(III) and Ru(II)-catalyzed site-selective C-H alkynylation of quinolones

DC Field Value Language
dc.contributor.authorDahye Kang-
dc.contributor.authorSungwoo Hong-
dc.date.available2016-01-07T09:14:25Z-
dc.date.created2015-05-18-
dc.date.issued2015-04-
dc.identifier.issn1523-7060-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/2067-
dc.description.abstractC2- and C5-alkynylated quinolone scaffolds are core structures of numerous biologically active molecules. Utilizing TIPS-EBX as an alkynylating agent, we have developed an efficient and site-selective C5 alkynylation of 4-quinolones that is directed by the weakly coordinating carbonyl group. In addition, Ru(II) catalyzed C2-selective alkynylation was successfully realized via N-pyrimidyl group-directed cross-couplings to access valuable C2-alkynylated 4-quinolones. This strategy provides direct access to the C2 or C5 alkynylated 4-quinolones. Furthermore, the reaction was applied to isoquinolones for C3-selective alkynylation. © 2015 American Chemical Society-
dc.languageENG-
dc.publisherAMER CHEMICAL SOC-
dc.titleRh(III) and Ru(II)-catalyzed site-selective C-H alkynylation of quinolones-
dc.typeArticle-
dc.type.rimsA-
dc.identifier.wosid000353314800031-
dc.identifier.scopusid2-s2.0-84928041937-
dc.description.wostc45-
dc.date.tcdate2018-10-01-
dc.date.scptcdate2018-10-01-
dc.contributor.affiliatedAuthorDahye Kang-
dc.contributor.affiliatedAuthorSungwoo Hong-
dc.identifier.bibliographicCitationORGANIC LETTERS, v.17, no.8, pp.1938 - 1941-
dc.description.scptc44-
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > Journal Papers (저널논문)
Files in This Item:
2015-OL-alkyne.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse