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유전체교정연구단
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Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites

DC Field Value Language
dc.contributor.authorJeongbin Park-
dc.contributor.authorSangsu Bae-
dc.contributor.authorJin Soo Kim-
dc.date.available2016-01-07T09:09:46Z-
dc.date.created2016-01-07-
dc.date.issued2015-12-
dc.identifier.issn1367-4803-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/1822-
dc.description.abstractWe present Cas-Designer, a user-friendly program to aid researchers in choosing appropriate target sites in a gene of interest for type II CRISPR/Cas-derived RNA-guided endonucleases, which are now widely used for biomedical research and biotechnology. Cas-Designer rapidly provides the list of all possible guide RNA sequences in a given input DNA sequence and their potential off-target sites including bulge-type sites in a genome of choice. In addition, the program assigns an out-of-frame score to each target site to help users choose appropriate sites for gene knockout. Cas-Designer shows the results in an interactive table and provides user-friendly filter functions.-
dc.description.uri1-
dc.language영어-
dc.publisherOXFORD UNIV PRESS-
dc.titleCas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000366630400024-
dc.identifier.scopusid2-s2.0-84950292610-
dc.identifier.rimsid21929ko
dc.date.tcdate2018-10-01-
dc.contributor.affiliatedAuthorJin Soo Kim-
dc.identifier.doi10.1093/bioinformatics/btv537-
dc.identifier.bibliographicCitationBIOINFORMATICS, v.31, no.24, pp.4014 - 4016-
dc.citation.titleBIOINFORMATICS-
dc.citation.volume31-
dc.citation.number24-
dc.citation.startPage4014-
dc.citation.endPage4016-
dc.date.scptcdate2018-10-01-
dc.description.wostc35-
dc.description.scptc37-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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