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유전체교정연구단
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Holotomography

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dc.contributor.authorKim, Geon-
dc.contributor.authorHugonnet, Herve-
dc.contributor.authorKim, Kyoohyun-
dc.contributor.authorLee, Jae-Hyuk-
dc.contributor.authorLee, Sung Sik-
dc.contributor.authorJeongmin Ha-
dc.contributor.authorLee, Chungha-
dc.contributor.authorPark, Hoewon-
dc.contributor.authorYoon, Ki-Jun-
dc.contributor.authorShin, Yongdae-
dc.contributor.authorCsucs, Gabor-
dc.contributor.authorHitchcock, Ian-
dc.contributor.authorMackinder, Luke-
dc.contributor.authorKim, Ji Hyang-
dc.contributor.authorHwang, Tae Hyun-
dc.contributor.authorLee, Seongsoo-
dc.contributor.authorO’Toole, Peter-
dc.contributor.authorBon-Kyoung Koo-
dc.contributor.authorGuck, Jochen-
dc.contributor.authorPark, YongKeun-
dc.date.accessioned2024-12-30T07:30:04Z-
dc.date.available2024-12-30T07:30:04Z-
dc.date.created2024-08-05-
dc.date.issued2024-07-
dc.identifier.issn2662-8449-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/16035-
dc.description.abstractHolotomography (HT) represents a 3D, label-free optical imaging methodology that leverages refractive index as an inherent quantitative contrast for imaging. This technique has recently seen notable advancements, creating novel opportunities for the comprehensive visualization and analysis of living cells and their subcellular organelles. It has manifested wide-ranging applications spanning cell biology, biophysics, microbiology and biotechnology, substantiating its vast potential. In this Primer, we elucidate the foundational physical principles underpinning HT, detailing its experimental implementations and providing case studies of representative research employing this methodology. We also venture into interdisciplinary territories, exploring how HT harmonizes with emergent technologies, such as regenerative medicine, 3D biology and organoid-based drug discovery and screening. Looking ahead, we engage in a prospective analysis of potential future trajectories for HT, discussing innovation-focused initiatives that may further elevate this field. We also propose possible future applications of HT, identifying opportunities for its integration into diverse realms of scientific research and technological development. © Springer Nature Limited 2024.-
dc.language영어-
dc.publisherSPRINGERNATURE-
dc.titleHolotomography-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.scopusid2-s2.0-85199775394-
dc.identifier.rimsid83759-
dc.contributor.affiliatedAuthorJeongmin Ha-
dc.contributor.affiliatedAuthorBon-Kyoung Koo-
dc.identifier.doi10.1038/s43586-024-00327-1-
dc.identifier.bibliographicCitationNature Reviews Methods Primers, v.4, no.1-
dc.relation.isPartOfNature Reviews Methods Primers-
dc.citation.titleNature Reviews Methods Primers-
dc.citation.volume4-
dc.citation.number1-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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