IBS Publications Repository: Discovery of Hepatitis C Virus NS3 Helicase Inhibitors by a Multiplexed, High-Throughput Helicase Activity Assay Based on Graphene Oxide

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IBS Publications RepositoryCenter for RNA Research(RNA 연구단)1. Journal Papers (저널논문)

Discovery of Hepatitis C Virus NS3 Helicase Inhibitors by a Multiplexed, High-Throughput Helicase Activity Assay Based on Graphene Oxide

DC Field	Value	Language
dc.contributor.author	Hongje Jang	-
dc.contributor.author	Soo-Ryoon Ryoo	-
dc.contributor.author	Young-Kwan Kim	-
dc.contributor.author	Soojin Yoon	-
dc.contributor.author	Henna Kim	-
dc.contributor.author	Sang Woo Han	-
dc.contributor.author	Byong-Seok Choi	-
dc.contributor.author	Dong-Eun Kim	-
dc.contributor.author	Dal-Hee Min	-
dc.date.available	2015-04-20T07:19:11Z	-
dc.date.created	2014-08-11	-
dc.date.issued	2013-02	-
dc.identifier.issn	1433-7851	-
dc.identifier.uri	https://pr.ibs.re.kr/handle/8788114/1396	-
dc.description.abstract	A GO-to solution: A simple graphene oxide (GO)-based assay to screen for selective inhibitors of a hepatitis C virus (HCV) helicase along with inhibitors of a severe acute respiratory syndrome coronavirus (SARS CoV) helicase was tested (see scheme). A single screen found five inhibitors highly selective for the HCV helicase orthologous to the SARS CoV helicase. Some of these hits were validated using the same GO-based assay. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.	-
dc.language	영어	-
dc.publisher	WILEY-V C H VERLAG GMBH	-
dc.title	Discovery of Hepatitis C Virus NS3 Helicase Inhibitors by a Multiplexed, High-Throughput Helicase Activity Assay Based on Graphene Oxide	-
dc.type	Article	-
dc.type.rims	ART	-
dc.identifier.wosid	000314998500041	-
dc.identifier.scopusid	2-s2.0-84873923411	-
dc.identifier.rimsid	121	ko
dc.date.tcdate	2018-10-01	-
dc.contributor.affiliatedAuthor	Dal-Hee Min	-
dc.identifier.doi	10.1002/anie.201209222	-
dc.identifier.bibliographicCitation	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.52, no.8, pp.2340 - 2344	-
dc.relation.isPartOf	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION	-
dc.citation.title	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION	-
dc.citation.volume	52	-
dc.citation.number	8	-
dc.citation.startPage	2340	-
dc.citation.endPage	2344	-
dc.date.scptcdate	2018-10-01	-
dc.description.wostc	35	-
dc.description.scptc	35	-
dc.description.journalClass	1	-
dc.description.journalClass	1	-
dc.description.journalRegisteredClass	scie	-
dc.description.journalRegisteredClass	scopus	-
dc.subject.keywordAuthor	biosensors	-
dc.subject.keywordAuthor	graphene oxide	-
dc.subject.keywordAuthor	helicases	-
dc.subject.keywordAuthor	high-throughput screening	-
dc.subject.keywordAuthor	multiplex assays	-