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Time-keeping and decision-making in living cells: Part I

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Title
Time-keeping and decision-making in living cells: Part I
Author(s)
Tyson, John J.; Csikasz-Nagy, Attila; Gonze, Didier; Jae Kyoung Kim; Santos, Silvia; Wolf, Jana
Publication Date
2022-04
Journal
Interface Focus, v.12, no.3
Publisher
Royal Society Publishing
Abstract
To survive and reproduce, a cell must process information from its environment and its own internal state and respond accordingly, in terms of metabolic activity, gene expression, movement, growth, division and differentiation. These signal–response decisions are made by complex networks of interacting genes and proteins, which function as biochemical switches and clocks, and other recognizable information-processing circuitry. This theme issue of Interface Focus (in two parts) brings together articles on time-keeping and decision-making in living cells—work that uses precise mathematical modelling of underlying molecular regulatory networks to understand important features of cell physiology. Part I focuses on time-keeping: mechanisms and dynamics of biological oscillators and modes of synchronization and entrainment of oscillators, with special attention to circadian clocks.
URI
https://pr.ibs.re.kr/handle/8788114/12944
DOI
10.1098/rsfs.2022.0011
ISSN
2042-8898
Appears in Collections:
Pioneer Research Center for Mathematical and Computational Sciences(수리 및 계산과학 연구단) > Biomedical Mathematics Group(의생명 수학 그룹) > 1. Journal Papers (저널논문)
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