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SCON—a Short Conditional intrON for conditional knockout with one-step zygote injection
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Wu, S.-H.S. | - |
| dc.contributor.author | Heetak Lee | - |
| dc.contributor.author | Szép-Bakonyi, R. | - |
| dc.contributor.author | Colozza, G. | - |
| dc.contributor.author | Boese, A. | - |
| dc.contributor.author | Gert, K.R. | - |
| dc.contributor.author | Hallay, N. | - |
| dc.contributor.author | Ji Hyun Lee | - |
| dc.contributor.author | Kim, J. | - |
| dc.contributor.author | Zhu, Y. | - |
| dc.contributor.author | Linssen, M.M. | - |
| dc.contributor.author | Pilat-Carotta, S. | - |
| dc.contributor.author | Hohenstein, P. | - |
| dc.contributor.author | Theussl, H.-C. | - |
| dc.contributor.author | Pauli, A. | - |
| dc.contributor.author | Bonkyoung Koo | - |
| dc.date.accessioned | 2023-01-26T02:25:11Z | - |
| dc.date.available | 2023-01-26T02:25:11Z | - |
| dc.date.created | 2022-12-17 | - |
| dc.date.issued | 2022-12 | - |
| dc.identifier.issn | 1226-3613 | - |
| dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/12497 | - |
| dc.description.abstract | The generation of conditional alleles using CRISPR technology is still challenging. Here, we introduce a Short Conditional intrON (SCON, 189 bp) that enables the rapid generation of conditional alleles via one-step zygote injection. In this study, a total of 13 SCON mouse lines were successfully generated by 2 different laboratories. SCON has conditional intronic functions in various vertebrate species, and its target insertion is as simple as CRISPR/Cas9-mediated gene tagging. © 2022, The Author(s). | - |
| dc.language | 영어 | - |
| dc.publisher | Springer Nature | - |
| dc.title | SCON—a Short Conditional intrON for conditional knockout with one-step zygote injection | - |
| dc.type | Article | - |
| dc.type.rims | ART | - |
| dc.identifier.wosid | 000896447100001 | - |
| dc.identifier.scopusid | 2-s2.0-85143622417 | - |
| dc.identifier.rimsid | 79482 | - |
| dc.contributor.affiliatedAuthor | Heetak Lee | - |
| dc.contributor.affiliatedAuthor | Ji Hyun Lee | - |
| dc.contributor.affiliatedAuthor | Bonkyoung Koo | - |
| dc.identifier.doi | 10.1038/s12276-022-00891-0 | - |
| dc.identifier.bibliographicCitation | Experimental and Molecular Medicine, v.54, no.12, pp.2188 - 2199 | - |
| dc.relation.isPartOf | Experimental and Molecular Medicine | - |
| dc.citation.title | Experimental and Molecular Medicine | - |
| dc.citation.volume | 54 | - |
| dc.citation.number | 12 | - |
| dc.citation.startPage | 2188 | - |
| dc.citation.endPage | 2199 | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalClass | 1 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalResearchArea | Research & Experimental Medicine | - |
| dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
| dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
| dc.subject.keywordPlus | GENE | - |
| dc.subject.keywordPlus | GENERATION | - |
| dc.subject.keywordPlus | RESOURCE | - |
- Appears in Collections:
- Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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