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Bonkyoung, Koo
유전체 교정 연구단
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Organoid Studies in COVID-19 Research

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Title
Organoid Studies in COVID-19 Research
Author(s)
Kim, J.; Bonkyoung Koo; Clevers, H.
Publication Date
2022-02
Journal
International Journal of Stem Cells, v.15, no.1, pp.3 - 13
Publisher
Sungkyunkwan University
Abstract
The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has completely changed human life for more than two years. Upon the emergence of this new lethal virus, multiple approaches were utilized to gain basic knowledge about its biology. Moreover, modern technologies, such as the organoid model system and next-generation sequencing, enabled us to rapidly establish strategies to tackle the disease, including vaccines and therapeutics. The recently developed organoid technology reflects human physiology more closely than other model systems. Coupled with its rapidness, high efficiency, and outstanding reliability, it has provided an opportunity to develop new drugs and understand the impact of the viral pathogen on the host. Recent findings using organoids have successfully revealed the cellular tropism of the virus in different organs and identified potential drug candidates that impact the disease. This review will summarize current achievements made with organoids in the fight against COVID-19. © 2022 by the Korean Society for Stem Cell Research
URI
https://pr.ibs.re.kr/handle/8788114/12066
DOI
10.15283/ijsc21251
ISSN
2005-3606
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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