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Publication Date2024-03
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors
Nahye Kim; Sungchul Choi; Sungjae Kim, et al
Nature Biotechnology, v.42, pp.484 - 497
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Publication Date2020-01
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells
Hui Kwon Kim; Sungtae Lee; Younggwang Kim, et al
NATURE BIOMEDICAL ENGINEERING, v.4, no.1, pp.111 - 124
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Publication Date2022-06
High-throughput functional evaluation of human cancer-associated mutations using base editors
Younggwang Kim; Seungho Lee; Soohyuk Cho, et al
Nature Biotechnology, v.40, no.6, pp.874 - 884
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Publication Date2023-07
Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9s
Sang-Yeon Seo; Seonwoo Min; Sungtae Lee, et al
Nature Methods, v.20, no.7, pp.999 - 1009
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Publication Date2023-05
Prediction of efficiencies for diverse prime editing systems in multiple cell types
Goosang Yu; Hui Kwon Kim; Jinman Park, et al
Cell, v.186, no.10, pp.2256 - 2272.e23
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Publication Date2020-11
Prediction of the sequence-specific cleavage activity of Cas9 variants
Nahye Kim; Hui Kwon Kim; Sungtae Lee, et al
NATURE BIOTECHNOLOGY, v.38, pp.1328 - 1336
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Publication Date2020-09
Sequence-specific prediction of the efficiencies of adenine and cytosine base editors
Myungjae Song; Hui Kwon Kim; Sungtae Lee, et al
Nature Biotechnology, v.38, no.9, pp.1037 - 1043
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Publication Date2019-11
SpCas9 activity prediction by DeepSpCas9, a deep learning–based model with high generalization performance
Hui Kwon Kim; Younggwang Kim; Sungtae Lee, et al
SCIENCE ADVANCES, v.5, no.11, pp.eaax9249
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Publication Date2024-07
SynDesign: web-based prime editing guide RNA design and evaluation tool for saturation genome editing
Jinman Park; Goosang Yu; Sang-Yeon Seo, et al
Nucleic Acids Research, v.52, no.W1, pp.W121 - W125