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Base Editing in Progeria

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Title
Base Editing in Progeria
Author(s)
Jin‑Soo Kim; Eriksson, Maria
Publication Date
2021-04-08
Journal
NEW ENGLAND JOURNAL OF MEDICINE, v.384, no.14, pp.1364 - 1366
Publisher
MASSACHUSETTS MEDICAL SOC
Abstract
The Hutchinson?Gilford progeria syndrome is an autosomal dominant disease caused by a single point mutation in LMNA, which encodes the lamin A and C proteins. Recent experiments have shown that life span in a mouse model of the disease was extended through DNA base editing.
URI
https://pr.ibs.re.kr/handle/8788114/9839
DOI
10.1056/NEJMcibr2100661
ISSN
0028-4793
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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