-
Publication Date2023-04
Deconstructive Pyridylation of Unstrained Cyclic Amines through a One-Pot Umpolung Approach
Seonghyeok Hong; Byeongseok Kweon; Wooseok Lee, et al
Organic Letters, v.25, no.15, pp.2722 - 2727
-
Publication Date2014-08
Development and Biological Evaluation of Potent and Selective c-KITD816V Inhibitors
Soyoung Lee; Lee, Hyunseung; Jinhee Kim, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.15, no.57, pp.6428 - 6443
-
Publication Date2017-03
Direct Phosphonation of Quinolinones and Coumarins Driven by the Photochemical Activity of Substrates and Products
Inwon Kim; Minsik Min; Dahye Kang, et al
ORGANIC LETTERS, v.19, no.6, pp.1394 - 1397
-
Publication Date2022-08
Discovery of a novel NUAK1 inhibitor against pancreatic cancer
Seo, Myeong-Seong; Jung, Kyung Hee; Kewon Kim, et al
BIOMEDICINE & PHARMACOTHERAPY, v.152
-
Publication Date2016-02
Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products
Park H.; Soyoung Lee; Sungwoo Hong
JOURNAL OF NATURAL PRODUCTS, v.79, no.2, pp.293 - 299
-
Publication Date2017-06
Discovery of EGF Receptor Inhibitors That Are Selective for the d746-750/T790M/C797S Mutant through Structure-Based de Novo Design
Park H.; Hoi-Yun Jung; Shinmee Mah, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.56, no.26, pp.7634 - 7638
-
Publication Date2019-01
Discovery of fluorescent 3-heteroarylcoumarin derivatives as novel inhibitors of anaplastic lymphoma kinase
Shinmee Mah; Jaebong Jang; Daesun Song, et al
ORGANIC & BIOMOLECULAR CHEMISTRY, v.17, no.1, pp.186 - 194
-
Publication Date2016-04
Discovery of Low Micromolar Dual Inhibitors for Wild Type and L1196M Mutant of Anaplastic Lymphoma Kinase through Structure-Based Virtual Screening
Shin, S; Shinmee Mah; Sungwoo Hong, et al
JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.56, no.4, pp.802 - 810
-
Publication Date2013-06
Discovery of Picomolar ABL Kinase Inhibitors Equipotent for Wild Type and T315I Mutant via Structure-Based de Novo Design
Hwangseo Park; Seunghee Hong; Jinhee Kim, et al
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.135, no.22, pp.8227 - 8237
-
Publication Date2015-11
Discovery of wrightiadione as a novel template for the TrkA kinase inhibitors
Yujeong Jeong; Sang Min Lim; Sungwoo Hong
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.22, pp.5186 - 5189
-
Publication Date2021-05-21
Divergent reactivity of sulfinates with pyridinium salts based on one- versus two-electron pathways
Myojeong Kim; Euna You; Seongjin Park, et al
CHEMICAL SCIENCE, v.12, no.19, pp.6629 - 6637
-
Publication Date2017-03
Efficient Synthesis of Anthraquinones from Diaryl Carboxylic Acids via Palladium(II)-Catalyzed and Visible Light-Mediated Transformations
Kiho Kim; Minsik Min; Sungwoo Hong
ADVANCED SYNTHESIS & CATALYSIS, v.359, no.5, pp.848 - 852
-
Publication Date2015-04
Efficient synthesis of frutinone A and its derivatives through palladium-catalyzed C-H activation/carbonylation
Yongje Shin; Changho Yoo; Youngtaek Moon, et al
CHEMISTRY-AN ASIAN JOURNAL, v.10, no.4, pp.878 - 881
-
Publication Date2022-04
Enantioselective functionalization at the C4 position of pyridinium salts through NHC catalysis
Hangyeol Choi; Gangadhar Rao Mathi; Seonghyeok Hong, et al
Nature Communications, v.13, no.1
-
Publication Date2023-08
Energy-transfer-induced [3+2] cycloadditions of N–N pyridinium ylides
Wooseok Lee; Yejin Koo; Hoimin Jung, et al
Nature Chemistry, v.15, no.8, pp.1091 - 1099
-
Publication Date2017-10
Fascaplysin exerts anti-cancer effects through the downregulation of survivin and HIF-1α and inhibition of VEGFR2 and TRKA
Taek-In Oh; Yoon-Mi Lee; Taek-Jin Nam, et al
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.18, no.10, pp.2074
-
Publication Date2020-11
Functionalization of Pyridinium Derivatives with 1,4-Dihydropyridines Enabled by Photoinduced Charge Transfer
Inwon Kim; Seongjin Park; Sunwoo Hong
ORGANIC LETTERS, v.22, no.21, pp.8730 - 8734
-
Publication Date2018-07
High-throughput chemical screening to discover new modulators of microRNA expression in living cells by using graphene-based biosensor
Soo-Ryoon Ryoo; Yeajee Yim; Young-Kwan Kim, et al
SCIENTIFIC REPORTS, v.8, pp.11413
-
Publication Date2014-10
HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy
Lee, Ju-Hee; Jung, Kyung Hee; Lee, Hyunseung, et al
ONCOTARGET, v.5, no.20, pp.10180 - 10197
-
Publication Date2018-09
HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis
Han-Hee Park; Se-Yeon Park; Shinmee Mah, et al
EXPERIMENTAL AND MOLECULAR MEDICINE, v.50, no.9, pp.125
-
Publication Date2020-06
HS-146, a novel phosphoinositide 3-kinase alpha inhibitor, induces the apoptosis and inhibits the metastatic ability of human breast cancer cells
Ok Hyeon Kim; Ju‑Hee Lee; Shinmee Mah, et al
INTERNATIONAL JOURNAL OF ONCOLOGY, v.56, no.6, pp.1509 - 1520
-
Publication Date2019-03
HS-173 as a novel inducer of RIP3-dependent necroptosis in lung cancer
Jung Hee Park; Kyung Hee Jung; Soo Jung Kim, et al
CANCER LETTERS, v.444, pp.94 - 104
-
Publication Date2016-11
HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer
Rumman M.; Jung K.H.; Fang Z., et al
ONCOTARGET, v.7, no.47, pp.78029 - 78047
-
Publication Date2015-01
HS-543 induces apoptosis of imatinib-resistant chronic myelogenous leukemia with T315I mutation
Kim S.J.; Jung K.H.; Yan H.H., et al
ONCOTARGET, v.6, no.3, pp.1507 - 1518
-
Publication Date2017-11
Identification of 4-Phenoxyquinoline Based Inhibitors for L1196M Mutant of Anaplastic Lymphoma Kinase by Structure-Based Design
Shinmee Mah; Jung Hee Park; Hoi-Yun Jung, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.60, no.22, pp.9205 - 9221
-
Publication Date2016-12
Identification of lead small molecule inhibitors of glycogen synthase kinase-3 beta using a fragment-linking strategy
Jinhee Kim; Yonghoon Moon; Sungwoo Hong
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.26, no.23, pp.5669 - 5673
-
Publication Date2015-11
Identification of β-lapachone analogs as novel MALT1 inhibitors to treat an aggressive subtype of diffuse large B-cell lymphoma
Sang Min Lim; Yujeong Jeong; Suhyun Lee, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.58, no.21, pp.8491 - 8502
-
Publication Date2020-11
Kinase and GPCR polypharmacological approach for the identification of efficient anticancer medicines
Hwangseo Park; Hoi-Yun Jung; Shinmee Mah, et al
ORGANIC & BIOMOLECULAR CHEMISTRY, v.18, no.41, pp.8402 - 8413
-
Publication Date2017-02
Metal- and oxidant-free S-P(O) bond construction: Via direct coupling of P(O)H with sulfinic acids
Youngtaek Moon; Yonghoon Moon; Hangyeol Choi, et al
GREEN CHEMISTRY, v.19, no.4, pp.1005 - 1013
-
Publication Date2018-11
Metal-free photocatalytic trifluoromethylative pyridylation of unactivated alkenes
Yu-Tao He; Dahye Kang; Inwon Kim, et al
GREEN CHEMISTRY, v.20, no.22, pp.5209 - 5214
-
Publication Date2022-10
N-Functionalized Pyridinium Salts: A New Chapter for Site-Selective Pyridine C-H Functionalization via Radical-Based Processes under Visible Light Irradiation
Myojeong Kim; Yejin Koo; Sungwoo Hong
ACCOUNTS OF CHEMICAL RESEARCH, v.55, no.20, pp.3043 - 3056
-
Publication Date2020-03
N-Heterocyclic carbene-catalyzed deaminative cross-coupling of aldehydes with Katritzky pyridinium salts
Inwon Kim; Honggu Im; Hyeonyeong Lee, et al
CHEMICAL SCIENCE, v.11, no.12, pp.3192 - 3197
-
Publication Date2023-06
Nickel-Catalyzed Kinetic Resolution of Racemic Unactivated Alkenes via Enantio-, Diastereo-, and Regioselective Hydroamination
Hyung-Joon Kang; Changseok Lee; Sungwoo Hong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.62, no.24
-
Publication Date2022-05
Nickel-Catalyzed Regio-and Enantioselective Hydroamination of Unactivated Alkenes Using Carbonyl Directing Groups
Changseok Lee; Hyung-Joon Kang; Huiyeong Seo, et al
Journal of the American Chemical Society, v.144, no.20, pp.9091 - 9100
-
Publication Date2024-01
NiH-catalyzed C-N bond formation: insights and advancements in hydroamination of unsaturated hydrocarbons
Changseok Lee; Hyung-Joon Kang; Sungwoo Hong
Chemical Science, v.2, no.2, pp.442 - 457
-
Publication Date2020-12
NiH-Catalyzed Proximal-Selective Hydroamination of Unactivated Alkenes
Jinwon Jeon; Changseok Lee; Huiyeong Seo, et al
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.142, no.48, pp.20470 - 20480
-
Publication Date2023-09
Nucleophilic C4-selective (hetero) arylation of pyridines for facile synthesis of heterobiaryls
Kewon Kim; Euna You; Sungwoo Hong
Frontiers in Chemistry, v.11
-
Publication Date2018-09
One-pot bifunctionalization of unactivated alkenes, P(O)-H compounds, and N-methoxypyridinium salts for the construction of β-pyridyl alkylphosphonates
Yu-Tao He; Joonghee Won; Jiyun Kim, et al
ORGANIC CHEMISTRY FRONTIERS, v.5, no.17, pp.2600 - 2608
-
Publication Date2013-05
One-pot catalysis of dehydrogenation of cyclohexanones to phenols and oxidative Heck coupling: expedient synthesis of coumarins
Donghee Kim; Minsik Min; Sung Woo Hong
CHEMICAL COMMUNICATIONS, v.49, no.38, pp.4021 - 4023
-
Publication Date2018-11
One-pot synthesis of 2-naphthols from nitrones and MBH adducts via decarboxylative N-O bond cleavage
Sang Hoon Han; Ashok Kumar Pandey; Heeyoung Lee, et al
ORGANIC CHEMISTRY FRONTIERS, v.5, no.22, pp.3210 - 3218
-
Publication Date2016-11
Optimization and biological evaluation of aminopyrimidine-based IκB kinase β inhibitors with potent anti-inflammatory effects
Yongje Shin; Sang Min Lim; Yan H.H., et al
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.123, pp.544 - 556
-
Publication Date2022-09
Oxidatively induced reactivity in Rh(iii)-catalyzed 7-azaindole synthesis: insights into the role of the silver additive
Ho Ryu; Bimal Pudasaini; Dasol Cho, et al
CHEMICAL SCIENCE, v.13, no.36, pp.10707 - 10714
-
Publication Date2016-07
Palladium(II)-Catalyzed Tandem Synthesis of Acenes Using Carboxylic Acids as Traceless Directing Groups
Kiho Kim; Dhananjayan Vasu; Honggu Im, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.55, no.30, pp.8652 - 8655
-
Publication Date2018-09
Palladium-Catalyzed Divergent Arylation of Triazolopyridines: A Computational Study
Deyaa I. AbuSalim; Sungwoo Hong; Mu-Hyun Baik
CHEMISTRY-AN ASIAN JOURNAL, v.13, no.17, pp.2505 - 2510
-
Publication Date2016-03
Palladium-Catalyzed Divergent Arylation with Triazolopyridines: One-Pot Synthesis of 6-Aryl-2-alpha-styrylpyridines
Youngtaek Moon; Soonhyung Kwon; Dahye Kang, et al
ADVANCED SYNTHESIS & CATALYSIS, v.358, no.6, pp.958 - 964
-
Publication Date2022-11
Photocatalytic Decarboxylative Pyridylation of Carboxylic Acids Using In Situ-Generated Amidyl Radicals as Oxidants
Changha Kim; Jinwook Jeong; Mari Vellakkaran, et al
ACS CATALYSIS, v.12, no.21, pp.13225 - 13233
-
Publication Date2023-11
Photocatalytic Enantioselective Hydrosulfonylation of α,β-Unsaturated Carbonyls with Sulfonyl Chlorides
Shi Cao; Doyoung Kim; Wooseok Lee, et al
Angewandte Chemie - International Edition, v.62, no.46
-
Publication Date2020-09
Photocatalytic Vicinal Aminopyridylation of Methyl Ketones by a Double Umpolung Strategy
Honggu Im; Wonjun Choi; Sungwoo Hong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.59, no.40, pp.17511 - 17516
-
Publication Date2020-01
Photochemical Carbopyridylation of Alkenes Using N-Alkenoxypyridinium Salts as Bifunctional Reagents
Gangadhar Rao Mathi; Yujin Jeong; Yonghoon Moon, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.59, no.5, pp.2049 - 2054
-
Publication Date2023-07
Photoinduced Carboarylation of Alkenes by Using Bifunctional Reagents
Minseok Kim; Kangjae Lee; Seonyul Kim, et al
SYNLETT, v.34, no.12, pp.1437 - 1441
-
Publication Date2023-06
Photoinduced difunctionalization with bifunctional reagents containing N-heteroaryl moieties
Wooseok Lee; Inyoung Park; Sungwoo Hong
SCIENCE CHINA-CHEMISTRY, v.66, no.6, pp.1688 - 1700
-
Publication Date2023-08
Photoinduced Electron Transfer from Xanthates to Acyl Azoliums: Divergent Ketone Synthesis via N-Heterocyclic Carbene Catalysis
Chang-Yin Tan; Minseok Kim; Sungwoo Hong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.62, no.32
-
Publication Date2020-12
Rational Computational Design of Fourth-Generation EGFR Inhibitors to Combat Drug-Resistant Non-Small Cell Lung Cancer
Park, Hwangseo; Hoi-Yun Jung; Kewon Kim, et al
International Journal of Molecular Sciences, v.21, no.23, pp.1 - 23
-
Publication Date2018-08
Reactivity of Morita-Baylis-Hillman Adducts in C-H Functionalization of (Hetero)aryl Nitrones: Access to Bridged Cycles and Carbazoles
Ashok Kumar Pandey; Dahye Kang; Sang Hoon Han, et al
ORGANIC LETTERS, v.20, no.15, pp.4632 - 4636
-
Publication Date2023-07
Regio- and Enantioselective Catalytic & delta;-C-H Amidation of Dioxazolones Enabled by Open-Shell Copper-Nitrenoid Transfer
Suhyeon Kim; Se Lin Song; Jianbo Zhang, et al
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.145, no.29, pp.16238 - 16248
-
Publication Date2021-12
Regio- and Stereoselective Functionalization Enabled by Bidentate Directing Groups
Jinwon Jeon; Changseok Lee; Inyoung Park, et al
Chemical Record, v.21, no.12, pp.3613 - 3627
-
Publication Date2022-01
Regiodivergent Conversion of Alkenes to Branched or Linear Alkylpyridines
Minseok Kim; Sanghoon Shin; Yejin Koo, et al
ORGANIC LETTERS, v.24, no.2, pp.708 - 713
-
Publication Date2018-12
Regiodivergent Ring-Opening Cross-Coupling of Vinyl Aziridines with Phosphorus Nucleophiles: Access to Phosphorus-Containing Amino Acid Derivatives
Dahye Kang; Taehwan Kim; Hyunpyo Lee, et al
ORGANIC LETTERS, v.20, no.23, pp.7571 - 7575
-
Publication Date2020-12
Regioselective C-H Functionalization of HeteroareneN-Oxides Enabled by a Traceless Nucleophile
Gangadhar Rao Mathi; Byeongseok Kweon; Yonghoon Moon, et al
Angewandte Chemie - International Edition, v.59, no.50, pp.22675 - 22683
-
Publication Date2015-12
Regioselective palladium(II)-catalyzed aerobic oxidative Heck-type C3 alkenylation of sulfocoumarins
Namhoon Kim; Minsik Min; Sungwoo Hong
ORGANIC CHEMISTRY FRONTIERS, v.2, no.12, pp.1621 - 1624