-
Publication Date2024-07
1,3-Difunctionalization of [1.1.1]propellane through iron-hydride catalyzed hydropyridylation
Changha Kim; Yuhyun Kim; Sungwoo Hong
Nature Communications, v.15, no.1
-
Publication Date2014-08
A copper-mediated cross-coupling approach for the synthesis of 3-heteroaryl quinolone and related analogues
Sanghye Shin; Yechan Kim; Kiho Kim, et al
ORGANIC & BIOMOLECULAR CHEMISTRY, v.12, no.30, pp.5719 - 5726
-
Publication Date2020-05
A human protein hydroxylase that accepts D-residues
Hwanho Choi; Adam P. Hardy; Thomas M. Leissing, et al
COMMUNICATIONS CHEMISTRY, v.3, no.1, pp.52
-
Publication Date2022-09
A novel DDR1 inhibitor enhances the anticancer activity of gemcitabine in pancreatic cancer
Ko, Soyeon; Jung, Kyung Hee; Yoon, Young -Chan, et al
AMERICAN JOURNAL OF CANCER RESEARCH, v.12, no.9, pp.4326 - 4342
-
Publication Date2014-03
A Pd-Catalyzed One-Pot dehydrogenative aromatization and Ortho-Functionalization Sequence of N-Acetyl Enamides
Jinhee Kim; Youngtaek Moon; Suhyun Lee, et al
CHEMICAL COMMUNICATIONS, v.50, no.24, pp.3227 - 3230
-
Publication Date2014-06
AgSbF6-controlled diastereodivergence in alkyne hydroarylation: facile access to Z- and E-alkenyl arenes
Minsik Min; Donghee Kim; Sung Woo Hong
CHEMICAL COMMUNICATIONS, v.50, no.59, pp.8028 - 8031
-
Publication Date2019-07
Allylic Acetals as Acrolein Oxonium Precursors in Tandem C−H Allylation and [3+2] Dipolar Cycloaddition
Heeyoung Lee; Dahye Kang; Sang Hoon Han, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.58, no.28, pp.9470 - 9474
-
Publication Date2016-10
Application of Fragment-Based de Novo Design to the Discovery of Selective Picomolar Inhibitors of Glycogen Synthase Kinase-3 Beta
Park H.; Yongje Shin; Jinhee Kim, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.59, no.19, pp.9018 - 9034
-
Publication Date2015-10
Asymmetric C-H Functionalization of Cyclopropanes Using an Isoleucine-NH2 Bidentate Directing Group
Jinhee Kim; Mikyung Sim; Namhoon Kim, et al
SYNTHESIS-STUTTGART, v.47, no.19, pp.A136 - A139
-
Publication Date2015-06
Asymmetric C–H functionalization of cyclopropanes using an isoleucine-NH2 bidentate directing group
Jinhee Kim; Mikyung Sim; Namhoon Kim, et al
CHEMICAL SCIENCE, v.6, no.6, pp.3611 - 3616
-
Publication Date2020-11-20
C2-Selective C-H Methylation of Heterocyclic N-Oxides with Sulfonium Ylides
Won An; Su Bin Choi; Namhoon Kim, et al
ORGANIC LETTERS, v.22, no.22, pp.9004 - 9009
-
Publication Date2022-12
C4-Selective C-H Borylation of Pyridinium Derivatives Driven by Electron Donor-Acceptor Complexes
Wonjun Choi; Minseok Kim; Kangjae Lee, et al
Organic Letters, v.24, no.51, pp.9452 - 9457
-
Publication Date2015-08
Catalyst Controlled Divergent C4/C8 Site-Selective C-H Arylation of Isoquinolones
Soyoung Lee; Shinmee Mah; Sungwoo Hong
ORGANIC LETTERS, v.17, no.15, pp.3864 - 3867
-
Publication Date2015-01
Computational design and discovery of nanomolar inhibitors of IκB kinase β
Park H.; Yongje Shin; Hyeonjeong Choe, et al
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.137, no.1, pp.337 - 348
-
Publication Date2024-05
Concurrent Optimizations of Efficacy and Blood-Brain Barrier Permeability in New Macrocyclic LRRK2 Inhibitors for Potential Parkinson’s Disease Therapeutics
Kewon Kim; Ahyoung Jang; Shin, Hochul, et al
Journal of Medicinal Chemistry, v.67, no.7647, pp.7647 - 7662
-
Publication Date2023-04
Deconstructive Pyridylation of Unstrained Cyclic Amines through a One-Pot Umpolung Approach
Seonghyeok Hong; Byeongseok Kweon; Wooseok Lee, et al
Organic Letters, v.25, no.15, pp.2722 - 2727
-
Publication Date2014-08
Development and Biological Evaluation of Potent and Selective c-KITD816V Inhibitors
Soyoung Lee; Lee, Hyunseung; Jinhee Kim, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.15, no.57, pp.6428 - 6443
-
Publication Date2017-03
Direct Phosphonation of Quinolinones and Coumarins Driven by the Photochemical Activity of Substrates and Products
Inwon Kim; Minsik Min; Dahye Kang, et al
ORGANIC LETTERS, v.19, no.6, pp.1394 - 1397
-
Publication Date2022-08
Discovery of a novel NUAK1 inhibitor against pancreatic cancer
Seo, Myeong-Seong; Jung, Kyung Hee; Kewon Kim, et al
BIOMEDICINE & PHARMACOTHERAPY, v.152
-
Publication Date2016-02
Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products
Park H.; Soyoung Lee; Sungwoo Hong
JOURNAL OF NATURAL PRODUCTS, v.79, no.2, pp.293 - 299
-
Publication Date2017-06
Discovery of EGF Receptor Inhibitors That Are Selective for the d746-750/T790M/C797S Mutant through Structure-Based de Novo Design
Park H.; Hoi-Yun Jung; Shinmee Mah, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.56, no.26, pp.7634 - 7638
-
Publication Date2019-01
Discovery of fluorescent 3-heteroarylcoumarin derivatives as novel inhibitors of anaplastic lymphoma kinase
Shinmee Mah; Jaebong Jang; Daesun Song, et al
ORGANIC & BIOMOLECULAR CHEMISTRY, v.17, no.1, pp.186 - 194
-
Publication Date2016-04
Discovery of Low Micromolar Dual Inhibitors for Wild Type and L1196M Mutant of Anaplastic Lymphoma Kinase through Structure-Based Virtual Screening
Shin, S; Shinmee Mah; Sungwoo Hong, et al
JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.56, no.4, pp.802 - 810
-
Publication Date2013-06
Discovery of Picomolar ABL Kinase Inhibitors Equipotent for Wild Type and T315I Mutant via Structure-Based de Novo Design
Hwangseo Park; Seunghee Hong; Jinhee Kim, et al
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.135, no.22, pp.8227 - 8237
-
Publication Date2015-11
Discovery of wrightiadione as a novel template for the TrkA kinase inhibitors
Yujeong Jeong; Sang Min Lim; Sungwoo Hong
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.22, pp.5186 - 5189
-
Publication Date2021-05-21
Divergent reactivity of sulfinates with pyridinium salts based on one- versus two-electron pathways
Myojeong Kim; Euna You; Seongjin Park, et al
CHEMICAL SCIENCE, v.12, no.19, pp.6629 - 6637
-
Publication Date2017-03
Efficient Synthesis of Anthraquinones from Diaryl Carboxylic Acids via Palladium(II)-Catalyzed and Visible Light-Mediated Transformations
Kiho Kim; Minsik Min; Sungwoo Hong
ADVANCED SYNTHESIS & CATALYSIS, v.359, no.5, pp.848 - 852
-
Publication Date2015-04
Efficient synthesis of frutinone A and its derivatives through palladium-catalyzed C-H activation/carbonylation
Yongje Shin; Changho Yoo; Youngtaek Moon, et al
CHEMISTRY-AN ASIAN JOURNAL, v.10, no.4, pp.878 - 881
-
Publication Date2022-04
Enantioselective functionalization at the C4 position of pyridinium salts through NHC catalysis
Hangyeol Choi; Gangadhar Rao Mathi; Seonghyeok Hong, et al
Nature Communications, v.13, no.1
-
Publication Date2023-08
Energy-transfer-induced [3+2] cycloadditions of N–N pyridinium ylides
Wooseok Lee; Yejin Koo; Hoimin Jung, et al
Nature Chemistry, v.15, no.8, pp.1091 - 1099
-
Publication Date2017-10
Fascaplysin exerts anti-cancer effects through the downregulation of survivin and HIF-1α and inhibition of VEGFR2 and TRKA
Taek-In Oh; Yoon-Mi Lee; Taek-Jin Nam, et al
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.18, no.10, pp.2074
-
Publication Date2020-11
Functionalization of Pyridinium Derivatives with 1,4-Dihydropyridines Enabled by Photoinduced Charge Transfer
Inwon Kim; Seongjin Park; Sunwoo Hong
ORGANIC LETTERS, v.22, no.21, pp.8730 - 8734
-
Publication Date2018-07
High-throughput chemical screening to discover new modulators of microRNA expression in living cells by using graphene-based biosensor
Soo-Ryoon Ryoo; Yeajee Yim; Young-Kwan Kim, et al
SCIENTIFIC REPORTS, v.8, pp.11413
-
Publication Date2014-10
HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy
Lee, Ju-Hee; Jung, Kyung Hee; Lee, Hyunseung, et al
ONCOTARGET, v.5, no.20, pp.10180 - 10197
-
Publication Date2018-09
HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis
Han-Hee Park; Se-Yeon Park; Shinmee Mah, et al
EXPERIMENTAL AND MOLECULAR MEDICINE, v.50, no.9, pp.125
-
Publication Date2020-06
HS-146, a novel phosphoinositide 3-kinase alpha inhibitor, induces the apoptosis and inhibits the metastatic ability of human breast cancer cells
Ok Hyeon Kim; Ju‑Hee Lee; Shinmee Mah, et al
INTERNATIONAL JOURNAL OF ONCOLOGY, v.56, no.6, pp.1509 - 1520
-
Publication Date2019-03
HS-173 as a novel inducer of RIP3-dependent necroptosis in lung cancer
Jung Hee Park; Kyung Hee Jung; Soo Jung Kim, et al
CANCER LETTERS, v.444, pp.94 - 104
-
Publication Date2016-11
HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer
Rumman M.; Jung K.H.; Fang Z., et al
ONCOTARGET, v.7, no.47, pp.78029 - 78047
-
Publication Date2015-01
HS-543 induces apoptosis of imatinib-resistant chronic myelogenous leukemia with T315I mutation
Kim S.J.; Jung K.H.; Yan H.H., et al
ONCOTARGET, v.6, no.3, pp.1507 - 1518
-
Publication Date2017-11
Identification of 4-Phenoxyquinoline Based Inhibitors for L1196M Mutant of Anaplastic Lymphoma Kinase by Structure-Based Design
Shinmee Mah; Jung Hee Park; Hoi-Yun Jung, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.60, no.22, pp.9205 - 9221
-
Publication Date2016-12
Identification of lead small molecule inhibitors of glycogen synthase kinase-3 beta using a fragment-linking strategy
Jinhee Kim; Yonghoon Moon; Sungwoo Hong
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.26, no.23, pp.5669 - 5673
-
Publication Date2015-11
Identification of β-lapachone analogs as novel MALT1 inhibitors to treat an aggressive subtype of diffuse large B-cell lymphoma
Sang Min Lim; Yujeong Jeong; Suhyun Lee, et al
JOURNAL OF MEDICINAL CHEMISTRY, v.58, no.21, pp.8491 - 8502
-
Publication Date2020-11
Kinase and GPCR polypharmacological approach for the identification of efficient anticancer medicines
Hwangseo Park; Hoi-Yun Jung; Shinmee Mah, et al
ORGANIC & BIOMOLECULAR CHEMISTRY, v.18, no.41, pp.8402 - 8413
-
Publication Date2017-02
Metal- and oxidant-free S-P(O) bond construction: Via direct coupling of P(O)H with sulfinic acids
Youngtaek Moon; Yonghoon Moon; Hangyeol Choi, et al
GREEN CHEMISTRY, v.19, no.4, pp.1005 - 1013
-
Publication Date2018-11
Metal-free photocatalytic trifluoromethylative pyridylation of unactivated alkenes
Yu-Tao He; Dahye Kang; Inwon Kim, et al
GREEN CHEMISTRY, v.20, no.22, pp.5209 - 5214
-
Publication Date2022-10
N-Functionalized Pyridinium Salts: A New Chapter for Site-Selective Pyridine C-H Functionalization via Radical-Based Processes under Visible Light Irradiation
Highly Cited Paper
Myojeong Kim; Yejin Koo; Sungwoo Hong
ACCOUNTS OF CHEMICAL RESEARCH, v.55, no.20, pp.3043 - 3056
-
Publication Date2020-03
N-Heterocyclic carbene-catalyzed deaminative cross-coupling of aldehydes with Katritzky pyridinium salts
Inwon Kim; Honggu Im; Hyeonyeong Lee, et al
CHEMICAL SCIENCE, v.11, no.12, pp.3192 - 3197
-
Publication Date2024-04
Nickel-Catalyzed Hydrofluorination in Unactivated Alkenes: Regio- and Enantioselective C-F Bond Formation
Changseok Lee; Minseok Kim; Seunghoon Ha, et al
Journal of the American Chemical Society, v.146, no.13, pp.9375 - 9384
-
Publication Date2023-06
Nickel-Catalyzed Kinetic Resolution of Racemic Unactivated Alkenes via Enantio-, Diastereo-, and Regioselective Hydroamination
Hyung-Joon Kang; Changseok Lee; Sungwoo Hong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.62, no.24
-
Publication Date2022-05
Nickel-Catalyzed Regio-and Enantioselective Hydroamination of Unactivated Alkenes Using Carbonyl Directing Groups
Changseok Lee; Hyung-Joon Kang; Huiyeong Seo, et al
Journal of the American Chemical Society, v.144, no.20, pp.9091 - 9100
-
Publication Date2024-05
Nickel/photoredox-catalyzed three-component silylacylation of acrylates via chlorine photoelimination
Yejin Koo; Sungwoo Hong
Chemical Science, v.2024, no.20, pp.7707 - 7713
-
Publication Date2024-01
NiH-catalyzed C-N bond formation: insights and advancements in hydroamination of unsaturated hydrocarbons
Changseok Lee; Hyung-Joon Kang; Sungwoo Hong
Chemical Science, v.2, no.2, pp.442 - 457
-
Publication Date2020-12
NiH-Catalyzed Proximal-Selective Hydroamination of Unactivated Alkenes
Jinwon Jeon; Changseok Lee; Huiyeong Seo, et al
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.142, no.48, pp.20470 - 20480
-
Publication Date2023-09
Nucleophilic C4-selective (hetero) arylation of pyridines for facile synthesis of heterobiaryls
Kewon Kim; Euna You; Sungwoo Hong
Frontiers in Chemistry, v.11
-
Publication Date2018-09
One-pot bifunctionalization of unactivated alkenes, P(O)-H compounds, and N-methoxypyridinium salts for the construction of β-pyridyl alkylphosphonates
Yu-Tao He; Joonghee Won; Jiyun Kim, et al
ORGANIC CHEMISTRY FRONTIERS, v.5, no.17, pp.2600 - 2608
-
Publication Date2013-05
One-pot catalysis of dehydrogenation of cyclohexanones to phenols and oxidative Heck coupling: expedient synthesis of coumarins
Donghee Kim; Minsik Min; Sung Woo Hong
CHEMICAL COMMUNICATIONS, v.49, no.38, pp.4021 - 4023
-
Publication Date2018-11
One-pot synthesis of 2-naphthols from nitrones and MBH adducts via decarboxylative N-O bond cleavage
Sang Hoon Han; Ashok Kumar Pandey; Heeyoung Lee, et al
ORGANIC CHEMISTRY FRONTIERS, v.5, no.22, pp.3210 - 3218
-
Publication Date2016-11
Optimization and biological evaluation of aminopyrimidine-based IκB kinase β inhibitors with potent anti-inflammatory effects
Yongje Shin; Sang Min Lim; Yan H.H., et al
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.123, pp.544 - 556
-
Publication Date2022-09
Oxidatively induced reactivity in Rh(iii)-catalyzed 7-azaindole synthesis: insights into the role of the silver additive
Ho Ryu; Bimal Pudasaini; Dasol Cho, et al
CHEMICAL SCIENCE, v.13, no.36, pp.10707 - 10714
-
Publication Date2016-07
Palladium(II)-Catalyzed Tandem Synthesis of Acenes Using Carboxylic Acids as Traceless Directing Groups
Kiho Kim; Dhananjayan Vasu; Honggu Im, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.55, no.30, pp.8652 - 8655