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Large‐Scale Synthesis and Medical Applications of Uniform‐Sized Metal Oxide Nanoparticles

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dc.contributor.authorHyek Jin Kwon-
dc.contributor.authorKwangsoo Shin-
dc.contributor.authorMin Soh-
dc.contributor.authorHogeun Chang-
dc.contributor.authorJonghoon Kim-
dc.contributor.authorJisoo Lee-
dc.contributor.authorGiho Ko-
dc.contributor.authorByung Hyo Kim-
dc.contributor.authorDokyoon Kim-
dc.contributor.authorTaeghwan Hyeon-
dc.date.available2019-01-30T02:00:46Z-
dc.date.created2019-01-11-
dc.date.issued2018-10-
dc.identifier.issn0935-9648-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/5425-
dc.description.abstractThanks to recent advances in the synthesis of high-quality inorganic nanoparticles, more and more types of nanoparticles are becoming available for medical applications. Especially, metal oxide nanoparticles have drawn much attention due to their unique physicochemical properties and relatively inexpensive production costs. To further promote the development and clinical translation of these nanoparticle-based agents, however, it is highly desirable to reduce unwanted interbatch variations of the nanoparticles because characterizing and refining each batch are costly, take a lot of effort, and, thus, are not productive. Large-scale synthesis is a straightforward and economic pathway to minimize this issue. Here, the recent achievements in the large-scale synthesis of uniform-sized metal oxide nanoparticles and their biomedical applications are summarized, with a focus on nanoparticles of transition metal oxides and lanthanide oxides, and clarifying the underlying mechanism for the synthesis of uniform-sized nanoparticles. Surface modification steps to endow hydrophobic nanoparticles with water dispersibility and biocompatibility are also briefly described. Finally, various medical applications of metal oxide nanoparticles, such as bioimaging, drug delivery, and therapy, are presented.© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim-
dc.description.uri1-
dc.language영어-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.subjectimaging, large-scale synthesis, metal oxides, nanomedicine, nanoparticles-
dc.titleLarge‐Scale Synthesis and Medical Applications of Uniform‐Sized Metal Oxide Nanoparticles-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000447377200005-
dc.identifier.scopusid2-s2.0-85044313686-
dc.identifier.rimsid66603-
dc.contributor.affiliatedAuthorHyek Jin Kwon-
dc.contributor.affiliatedAuthorKwangsoo Shin-
dc.contributor.affiliatedAuthorMin Soh-
dc.contributor.affiliatedAuthorHogeun Chang-
dc.contributor.affiliatedAuthorJonghoon Kim-
dc.contributor.affiliatedAuthorJisoo Lee-
dc.contributor.affiliatedAuthorGiho Ko-
dc.contributor.affiliatedAuthorByung Hyo Kim-
dc.contributor.affiliatedAuthorDokyoon Kim-
dc.contributor.affiliatedAuthorTaeghwan Hyeon-
dc.identifier.doi10.1002/adma.201704290-
dc.identifier.bibliographicCitationADVANCED MATERIALS, v.30, no.42, pp.1704290-
dc.citation.titleADVANCED MATERIALS-
dc.citation.volume30-
dc.citation.number42-
dc.citation.startPage1704290-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > 1. Journal Papers (저널논문)
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