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Electrogenerated chemiluminescence of lucigenin at mesoporous platinum electrode and its biosensing application to superoxide dismutase

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dc.contributor.authorSungju Nam-
dc.contributor.authorWon-Yong Lee-
dc.date.available2018-07-18T02:07:11Z-
dc.date.created2018-02-14-
dc.date.issued2018-01-
dc.identifier.issn1572-6657-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/4715-
dc.description.abstractThe electrogenerated chemiluminescence (ECL) behavior of lucigenin on a mesoporous platinum electrode has been studied in neutral aqueous solution (pH 7). The present mesoporous Pt electrode with highly enlarged surface area, with a roughness factor of 301, exhibits much larger electrochemical responses for the oxidation of water and the reduction of molecular oxygen, which leads to much larger lucigenin ECL responses related to the anodic and cathodic electrochemical reactions even in a neutral solution, compared to those at a bare Pt electrode. Based on the capability of superoxide dismutase (SOD) to inhibit lucigenin ECL by scavenging superoxide anions, a highly sensitive ECL bioassay for SOD has been developed with a linear dynamic range of 5.75 x 10(-10) M-3.00 x 10(-6) M and a detection limit of 3.49 x 10(-10) M (S/N = 3), which is much lower than those obtained with other detection methods © 2017 Published by Elsevier B.V.-
dc.description.uri1-
dc.language영어-
dc.publisherELSEVIER SCIENCE SA-
dc.subjectElectrogenerated chemiluminescence-
dc.subjectLucigenin-
dc.subjectMesoporous platinum electrode-
dc.subjectSuperoxide anion-
dc.subjectSuperoxide dismutase-
dc.titleElectrogenerated chemiluminescence of lucigenin at mesoporous platinum electrode and its biosensing application to superoxide dismutase-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000423650000009-
dc.identifier.scopusid2-s2.0-85037076736-
dc.identifier.rimsid62208ko
dc.date.tcdate2018-10-01-
dc.contributor.affiliatedAuthorSungju Nam-
dc.contributor.affiliatedAuthorWon-Yong Lee-
dc.identifier.doi10.1016/j.jelechem.2017.11.056-
dc.identifier.bibliographicCitationJOURNAL OF ELECTROANALYTICAL CHEMISTRY, v.808, pp.59 - 64-
dc.citation.titleJOURNAL OF ELECTROANALYTICAL CHEMISTRY-
dc.citation.volume808-
dc.citation.startPage59-
dc.citation.endPage64-
dc.date.scptcdate2018-10-01-
dc.description.scptc0-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordPlusDOWNS-SYNDROME-
dc.subject.keywordPlusELECTROCHEMILUMINESCENCE-
dc.subject.keywordPlusMANGANESE-
dc.subject.keywordPlusOVEREXPRESSION-
dc.subject.keywordPlusENHANCEMENT-
dc.subject.keywordPlusREDUCTION-
dc.subject.keywordPlusGROWTH-
dc.subject.keywordPlusOXYGEN-
dc.subject.keywordPlusFILM-
dc.subject.keywordAuthorElectrogenerated chemiluminescence-
dc.subject.keywordAuthorLucigenin-
dc.subject.keywordAuthorMesoporous platinum electrode-
dc.subject.keywordAuthorSuperoxide anion-
dc.subject.keywordAuthorSuperoxide dismutase-
Appears in Collections:
Center for Nanomedicine (나노의학 연구단) > 1. Journal Papers (저널논문)
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23.Journal of Electroanalytical Chemistry 808, 59-64, (2018).pdfDownload

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