Excitation/Inhibition Imbalance in Animal Models of Autism Spectrum DisordersHighly Cited Paper
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Eunee Lee | - |
dc.contributor.author | Jiseok Lee | - |
dc.contributor.author | Eunjoon Kim | - |
dc.date.available | 2017-10-19T02:29:38Z | - |
dc.date.created | 2017-09-28 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 0006-3223 | - |
dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/3886 | - |
dc.description.abstract | Imbalances between excitation and inhibition in synaptic transmission and neural circuits have been implicated in autism spectrum disorders. Excitation and inhibition imbalances are frequently observed in animal models of autism spectrum disorders, and their correction normalizes key autistic-like phenotypes in these animals. These results suggest that excitation and inhibition imbalances may contribute to the development and maintenance of autism spectrum disorders and represent an important therapeutic target. (c) 2016 Society of Biological Psychiatry. This is an open access article under the CC BY-NC-ND license | - |
dc.description.uri | 1 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | Autism spectrum disorders | - |
dc.subject | Circuit | - |
dc.subject | Excitation/inhibition balance | - |
dc.subject | Mouse models | - |
dc.subject | Psychiatric disorders | - |
dc.subject | Synapse | - |
dc.title | Excitation/Inhibition Imbalance in Animal Models of Autism Spectrum Disorders | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.wosid | 000400335100005 | - |
dc.identifier.scopusid | 2-s2.0-84979538965 | - |
dc.identifier.rimsid | 60312 | ko |
dc.date.tcdate | 2018-10-01 | - |
dc.contributor.affiliatedAuthor | Eunee Lee | - |
dc.contributor.affiliatedAuthor | Eunjoon Kim | - |
dc.identifier.doi | 10.1016/j.biopsych.2016.05.011 | - |
dc.identifier.bibliographicCitation | BIOLOGICAL PSYCHIATRY, v.81, no.10, pp.838 - 847 | - |
dc.citation.title | BIOLOGICAL PSYCHIATRY | - |
dc.citation.volume | 81 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 838 | - |
dc.citation.endPage | 847 | - |
dc.date.scptcdate | 2018-10-01 | - |
dc.description.wostc | 33 | - |
dc.description.scptc | 34 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |