BROWSE

Related Scientist

CNIR's photo.

CNIR
뇌과학 이미징 연구단
more info

ITEM VIEW & DOWNLOAD

D* from diffusion MRI reveals a correspondence between ventricular cerebrospinal fluid volume and flow in the ischemic rodent model

DC Field Value Language
dc.contributor.authorJang, M.-
dc.contributor.authorHan, S.-
dc.contributor.authorCho, H.-
dc.date.accessioned2022-07-29T07:45:23Z-
dc.date.available2022-07-29T07:45:23Z-
dc.date.created2022-07-25-
dc.date.issued2022-04-
dc.identifier.issn0271-678X-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/12047-
dc.description.abstractQuantitative measurement of cerebrospinal fluid (CSF) flow and volume and longitudinal monitoring of CSF dynamics provide insights into the compensatory characteristics of post-stroke CSF. In this study, we compared the MRI pseudo-diffusion index (D*) of live and sacrificed rat brains to confirm the effect of ventricular CSF flow on diffusion signals. We observed the relationship between the CSF peak velocities and D* through Monte Carlo (MC) simulations to further understand the source of D* contrast. We also determined the dominant CSF flow using D* in three directions. Finally, we investigated the dynamic evolutions of ventricular CSF flow and volume in a stroke rat model (n = 8) from preoperative to up to 45 days after surgery and determined the correlation between ventricular CSF volume and flow. MC simulations showed a strong positive correlation between the CSF peak velocity and D* (r = 0.99). The dominant CSF flow variations in the 3D ventricle could be measured using the maximum D* map. A longitudinal positive correlation between ventricular CSF volume and D* was observed in the lateral (r = 0.74) and ventral-third (r = 0.81) ventricles, respectively. The directional D* measurements provide quantitative CSF volume and flow information, which would provide useful insights into ischemic stroke with diffusion MRI. © The Author(s) 2021.-
dc.language영어-
dc.publisherSAGE Publications Ltd-
dc.titleD* from diffusion MRI reveals a correspondence between ventricular cerebrospinal fluid volume and flow in the ischemic rodent model-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000721951100001-
dc.identifier.scopusid2-s2.0-85119621783-
dc.identifier.rimsid78562-
dc.contributor.affiliatedAuthorHan, S.-
dc.identifier.doi10.1177/0271678X211060741-
dc.identifier.bibliographicCitationJournal of Cerebral Blood Flow and Metabolism, v.42, no.4, pp.572 - 583-
dc.relation.isPartOfJournal of Cerebral Blood Flow and Metabolism-
dc.citation.titleJournal of Cerebral Blood Flow and Metabolism-
dc.citation.volume42-
dc.citation.number4-
dc.citation.startPage572-
dc.citation.endPage583-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordAuthorcerebrospinal fluid flow-
dc.subject.keywordAuthorCerebrospinal fluid volume-
dc.subject.keywordAuthordiffusion MRI-
dc.subject.keywordAuthorischemic stroke-
dc.subject.keywordAuthorsubacute stage-
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse