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Publication Date2022-02
Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases
Hyewon Jang; Dong Hyun Jo; Chang Sik Cho, et al
Nature Biomedical Engineering, v.6, no.2, pp.181 - 194
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Publication Date2019-05
En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements
Hyeon J. Lee; Ramu Gopalappa; Hongjae Sunwoo, et al
NUCLEIC ACIDS RESEARCH, v.47, no.8, pp.3875 - 3887
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Publication Date2024-07
In vivo adenine base editing rescues adrenoleukodystrophy in a humanized mouse model
Ramu Gopalappa; MinYoung Lee; Globinna Kim, et al
Molecular Therapy, v.32, no.7, pp.2190 - 2206
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Publication Date2022-01
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model
Byunghwa Noh; John Hoon Rim; Ramu Gopalappa, et al
Theranostics, v.12, no.5, pp.2465 - 2482
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Publication Date2018-07
Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption
Ramu Gopalappa; Bharathi Suresh; Suresh Ramakrishna, et al
NUCLEIC ACIDS RESEARCH, v.46, no.12, pp.e71