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Publication Date2018-08
Large deletions induced by Cas9 cleavage, Ma et al. reply
Hong Ma; Nuria Marti-Gutierrez; Sang-Wook Park, et al
NATURE, v.560, no.7717, pp.E10 - E23
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Publication Date2023-03
Limitations of gene editing assessments in human preimplantation embryos
Liang, Dan; Mikhalchenko, Aleksei; Ma, Hong, et al
Nature Communications, v.14, no.1
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Publication Date2019-01
Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus
Dong Hyun Jo; Taeyoung Koo; Chang Sik Cho, et al
MOLECULAR THERAPY, v.27, no.1, pp.130 - 136
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Publication Date2018-12
Machine learning finds Cas9-edited genotypes
Sangsu Bae; Jin-Soo Kim
NATURE BIOMEDICAL ENGINEERING, v.2, no.12, pp.892 - 893
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Publication Date2015-06
Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9
Taeyoung Koo; Jungjoon Lee; Jin Soo Kim
MOLECULES AND CELLS, v.38, no.6, pp.475 - 481
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Publication Date2018-03
Microbial warfare against viruses
Jin Soo Kim
SCIENCE, v.359, no.6379, pp.993
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Publication Date2014-07
Microhomology-based choice of Cas9 nuclease target sites
Sangsu Bae; Jiyeon Kweon; Heon Seok Kim, et al
NATURE METHODS, v.11, no.7, pp.705 - 706
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Publication Date2021-02-19
Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases
Hyunji Lee; Seonghyun Lee; Gayoung Baek, et al
NATURE COMMUNICATIONS, v.12, no.1
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Publication Date2017-08
Myofibroblast in the ligamentum flavum hypertrophic activity
Junseok W. Hur; Taegeun Bae; Sunghyeok Ye, et al
EUROPEAN SPINE JOURNAL, v.26, no.8, pp.2021 - 2030
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Publication Date2015-09
Non-GMO genetically edited crop plants
Chidanada Nagamangala Kanchiswamy; Mickael Malnoy; Riccardo Velasco, et al
TRENDS IN BIOTECHNOLOGY, v.33, no.9, pp.489 - 491
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Publication Date2022-01
Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases
Highly Cited Paper
Kayeong Lim; Sung-Ik Cho; Jin-Soo Kim
NATURE COMMUNICATIONS, v.13, no.1
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Publication Date2021-06
Off-the-Shelf, Immune-Compatible Human Embryonic Stem Cells Generated Via CRISPR-Mediated Genome Editing
Annie Kim; Kun-Gu Lee; Yeongbeen Kwon, et al
STEM CELL REVIEWS AND REPORTS, v.17, no.3, pp.1053 - 1067
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Publication Date2021-07-02
PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing
Hwang, Gue-Ho; Jeong, You Kyeong; Habib, Omer, et al
NUCLEIC ACIDS RESEARCH, v.49, no.W1, pp.W499 - W504
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Publication Date2022-10
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia
Ottaviano, Giorgio; Georgiadis, Christos; Gkazi, Soragia Athina, et al
Science Translational Medicine, v.14, no.668
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Publication Date2018-03
Precision genome engineering through adenine and cytosine base editing
Jin Soo Kim
NATURE PLANTS, v.4, no.3, pp.148 - 151
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Publication Date2018-07
Precision genome engineering through adenine base editing in plants
Highly Cited Paper
Beum-Chang Kang; Jae-Young Yun; Sang-Tae Kim, et al
NATURE PLANTS, v.4, no.7, pp.427 - 431
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Publication Date2023-03
Precision mitochondrial DNA editing with high-fidelity DddA-derived base editors
Seonghyun Lee; Hyunji Lee; Ga Young Baek, et al
NATURE BIOTECHNOLOGY, v.41, no.3, pp.378 - 186
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Publication Date2023-03
Prime editing with genuine Cas9 nickases minimizes unwanted indels
Jaesuk Lee; Kayeong Lim; Annie Kim, et al
Nature Communications, v.14, no.1
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Publication Date2022-07
Production of MSTN-mutated cattle without exogenous gene integration using CRISPR-Cas9
Gim, Gyeong-Min; Kwon, Dong-Hyeok; Eom, Kyeong-Hyun, et al
BIOTECHNOLOGY JOURNAL, v.17, no.7
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Publication Date2021-01
Profiling genome-wide specificity of CRISPR-Cas9 using digenome-seq
Daesik Kim; Jin-Soo Kim
Methods in molecular biology (Clifton, N.J.), v.2162, pp.233 - 242
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Publication Date2020-05
Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages
Yi Rang Na; Jung Won Kwon; Da Young Kim, et al
CELL REPORTS, v.31, no.6, pp.107643
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Publication Date2022-05
Rationally designed nanoparticle delivery of Cas9 ribonucleoprotein for effective gene editing
Chae, Se-Youl; Euihwan Jeong; Kang, Seounghun, et al
Journal of Controlled Release, v.345, pp.108 - 119
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Publication Date2020-05
Recent advances in genome editing of stem cells for drug discovery and therapeutic application
Jaesuk Lee; Delger Bayarsaikhan; Govigerel Bayarsaikhan, et al
PHARMACOLOGY & THERAPEUTICS, v.209, pp.107501
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Publication Date2017-11
Rescue of high-specificity Cas9 variants using sgRNAs with matched 5 ' nucleotides
Sojung Kim; Taegeun Bae; Jaewoong Hwang, et al
GENOME BIOLOGY, v.18, no.1, pp.218
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Publication Date2018-04
Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo”
Sang-Tae Kim; Jeongbin Park; Dae Sik Kim, et al
NATURE METHODS, v.15, no.4, pp.239 - 240
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Publication Date2014-07
RNA-Guided Genome Editing in Drosophila with the Purified Cas9 Protein
Jeong-Soo Lee; Su-Jin Kwak; Jungeun Kim, et al
G3-GENES GENOMES GENETICS, v.4, no.7, pp.1291 - 1295
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Publication Date2018-06
Science Stars of East Asia
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Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression
Taeyoung Koo; A-Rum Yoon; Hee-Yeon Cho, et al
NUCLEIC ACIDS RESEARCH, v.45, no.13, pp.7897 - 7908
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Publication Date2016-11
SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells
He M.; Yuan H.; Tan B., et al
ONCOTARGET, v.7, no.46, pp.75698 - 75711
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Publication Date2016-07
SITE-DIRECTED MUTAGENESIS IN PETUNIA X HYBRIDA PROTOPLAST SYSTEM USING DIRECT DELIVERY OF PURIFIED RECOMBINANT CAS9 RIBONUCLEOPROTEINS
Subburaj S; Chung SJ; Choongil Lee, et al
PLANT CELL REPORTS, v.35, no.7, pp.1535 - 1544
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Publication Date2018-07
Sometimes you’re the scooper, and sometimes you get scooped: How to turn both into something good
Jin-Soo Kim; Jacob E. Corn
PLOS BIOLOGY, v.16, no.7, pp.e2006843
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Publication Date2018-04
Structural insights into the apo-structure of Cpf1 protein from Francisella novicida
Min, K; Yoon, H; Jo, I, et al
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.498, no.4, pp.775 - 781
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Publication Date2016-11
Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
Toungbin Lim; So Young Bak; Keewon Sung, et al
NATURE COMMUNICATIONS, v.7, pp.13350
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Publication Date2013-12
TALEN-based knockout library for human microRNAs
Young-Kook Kim; Gabbine Wee; Joha Park, et al
NATURE STRUCTURAL & MOLECULAR BIOLOGY, v.20, no.12, pp.1458 - 1464
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Publication Date2021-12
Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library
Naoki Miyamoto; Go, Young-Hyun; Larissa Miasiro Ciaramicoli, et al
RSC Chemical Biology, v.2, no.6, pp.1590 - 1593
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Publication Date2022-05
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases
Highly Cited Paper
Sung-Ik Cho; Seonghyun Lee; Young Geun Mok, et al
Cell, v.185, no.10, pp.1764 - 1776.e12
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Publication Date2022-12
Targeted A-to-G base editing of chloroplast DNA in plants
Young Gun Mok; Sung Hyun Hong; Su Ji Bae, et al
Nature Plants, v.8, no.12, pp.1378 - 1384
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Publication Date2015-12
Targeted Genome Editing for Crop Improvement
Hyeran Kim; Sang-Tae Kim; Sang-Gyu Kim, et al
Plant Breeding and Biotechnology, v.3, no.4, pp.283 - 290
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Publication Date2014-06
Targeted inversion and reversion of the blood coagulation factor 8 gene in iPS cells using TALENs
Chul-Yong Park; Jungeun Kim; Jiyeon Kweon, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.111, no.25, pp.9253 - 9258
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Publication Date2018-01
Targeted knockout of a chemokine-like gene increases anxiety and fear responses
Jung-Hwa Choi; Yun-Mi Jeong; Sujin Kim, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.115, no.5, pp.E1041 - E1050
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Publication Date2016-08
Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins
Junho K Hur; Kyoungmi Kim; Kyung Wook Been, et al
NATURE BIOTECHNOLOGY, v.34, no.8, pp.807 - 808
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Publication Date2019-01
TECHNOLOGIES TO WATCH IN 2019
Teichmann, S; Jinsoo Kim; Zhuang, XW, et al
NATURE, v.565, no.7740, pp.521 - 523
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Publication Date2021-04-13
The efficacy of CRISPR-mediated cytosine base editing with the RPS5a promoter in Arabidopsis thaliana
Minkyung Choi; Jae‑Young Yun; Jun‑Hyuk Kim, et al
Scientific Reports, v.11, no.1, pp.1 - 9
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Publication Date2021-11
The functional association of acqos/victr with salt stress resistance in arabidopsis thaliana was confirmed by crispr-mediated mutagenesis
Kim, Sang-Tae; Minkyung Choi; Su-Ji Bae, et al
International Journal of Molecular Sciences, v.22, no.21
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Publication Date2020-10
The road ahead in genetics and genomics
Amy L. McGuire; Stacey Gabriel; Sarah A. Tishkoff, et al
NATURE REVIEWS GENETICS, v.21, no.10, pp.581 - 596
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Publication Date2018-10
Towards therapeutic base editing
Huiyun Seo; Jin-Soo Kim
NATURE MEDICINE, v.24, no.10, pp.1493 - 1495
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Publication Date2022-06
Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice
Whisenant, Daniel; Kayeong Lim; Revechon, Gwladys, et al
NATURE COMMUNICATIONS, v.13, no.1
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Publication Date2018-08
Unexpected CRISPR on-target effects
Hyunji Lee; Jin-Soo Kim
NATURE BIOTECHNOLOGY, v.36, no.8, pp.703 - +
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Publication Date2019-06
Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate
Beomsue Kim; Masahiro Fukuda; Jung-Yeol Lee, et al
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.58, no.24, pp.7972 - 7976
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Publication Date2021-01
Web-based CRISPR Toolkits: Cas-OFFinder, cas-designer, and cas-analyzer
Gue-Ho Hwang; Jin-Soo Kim; Sangsu Bae
Methods in molecular biology (Clifton, N.J.), v.2162, pp.23 - 33
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Publication Date2018-12
Web-based design and analysis tools for CRISPR base editing
Hwang G.-H.; Park J.; Kayeong Lim, et al
BMC BIOINFORMATICS, v.19, no.1, pp.542
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Publication Date2016-04
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